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VSIG4

VSIG4 詳細

英語名	V-set and immunoglobulin domain-containing protein 4	市販薬剤の数	0
治験薬の数	1	ターゲットの別称	Protein Z39Ig，CRIg，Z39IG
研究＆開発段階	Phase 1 Clinical

英語名	V-set and immunoglobulin domain-containing protein 4
ターゲットの別称	Protein Z39Ig，CRIg，Z39IG
市販薬剤の数	0
治験薬の数	1
研究＆開発段階	Phase 1 Clinical

VSIG4 製品リスト

属性
Protein (2)
製品ライブラリ
オンライン (2)
種
Human (2)
タグ
His Tag (1)His Tag & Avi Tag (1)
マーカー
Unconjugated (1)Biotin-labeled (1)

製品番号	種	発現システム	製品説明	タンパク質の構造	純度	特性
VS4-H5226	Human	HEK293	Human VSIG4 Protein, His Tag
VS4-H82E3	Human	HEK293	Biotinylated Human VSIG4 Protein, His,Avitag™ (MALS verified)

総数量2

VSIG4バックグランド

V-set and immunoglobulin domain-containing protein 4 (VSIG4) is also known as Protein Z39Ig, is a type I transmembrane glycoprotein. VSIG4 is a B7 family-related protein and an Ig superfamily member. VSIG4 contains two Ig-like (immunoglobulin-like) domains. VSIG4 is abundantly expressed in several fetal tissues. In adult tissues, the highest expression of VSIG4 is in lung and placenta. VSIG4 functions as a negative regulator of T cell activation, and may be involved in the maintenance of peripheral T cell tolerance, and is also identified as a potent suppressor of established inflammation. VSIG4 is a phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production.