Biotinylated Human IL-21 R Protein, Fc,Avitag™ (MALS verified)

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製品番号/仕様
価格
数量
ILR-H82F7-25ug
$360.00
ILR-H82F7-200ug
$1420.00
ETA of in-stock products:2 business days
総アイテム数 製品金額$ 0

製品詳細

  • Synonyms

    IL21R, CD360, NILR

  • Source

    Biotinylated Human IL-21 R Protein, Fc,Avitag (ILR-H82F7) is expressed from human 293 cells (HEK293). It contains AA Cys 20 - Pro 236 (Accession # Q9HBE5-1).

    Predicted N-terminus: Cys 20

    Request for sequence
  • Molecular Characterization

    IL-21 R Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™).

    The protein has a calculated MW of 53.1 kDa. The protein migrates as 65 -80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Labeling

    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

  • Protein Ratio

    Passed as determined by the HABA assay / binding ELISA.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Shipping and Storage

    This product is shipped at ambient temperature.

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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データ表示

  • SDS-PAGE

    IL-21 R SDS-PAGE

    Biotinylated Human IL-21 R Protein, Fc,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    IL-21 R SEC-MALS

    The purity of Biotinylated Human IL-21 R Protein, Fc,Avitag (Cat. No. ILR-H82F7) is more than 85% and the molecular weight of this protein is around 120-140 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     IL-21 R ELISA

    Immobilized Human IL-21, premium grade (Cat. No. IL1-H5213) at 5 μg/mL (100 μL/well) can bind Biotinylated Human IL-21 R Protein, Fc,Avitag (Cat. No. ILR-H82F7) with a linear range of 2-39 ng/mL (QC tested).

    Protocol

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バックグランド

Interleukin-21 receptor (IL21R) is also known as CD antigen CD360, Novel interleukin receptor (NILR), is a receptor for interleukin-21 and belongs to the type I cytokine receptor family or type 4 subfamily. IL21R contains two fibronectin type-III domains. IL21R is selectively expressed in lymphoid tissues and most highly expressed in thymus and spleen. IL21R transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells.

最新の進展

 
医薬品開発の進捗
  • 英語名:

    Interleukin 21 Receptor

  • カテゴリ:

  • 市販の医薬品数:

    0 詳細

  • 治験医薬品数:

    2 詳細

  • 最新の開発ステージ:

    Phase 1 Clinical

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