製品詳細
Synonyms
IL6R, CD126, IL-6R-1, IL-6RA, IL6RA, IL-6R-alpha, IL6RQ, gp80
Source
Biotinylated Human IL-6 R alpha, Avitag,His Tag (CD6-H82E8) is expressed from human 293 cells (HEK293). It contains AA Leu 20 - Pro 365 (Accession # P08887-1).
Predicted N-terminus: Leu 20
Request for sequenceMolecular Characterization

Other Tags and Version Biotin & Other Labeled Version
This protein carries an Avi tag (Avitag™) at the C-terminus, followed by a polyhistidine tag.
The protein has a calculated MW of 41.7 kDa. The protein migrates as 52-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Labeling
Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
Protein Ratio
Passed as determined by the HABA assay / binding ELISA.
Purity
>95% as determined by SDS-PAGE.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Shipping and Storage
This product is shipped at ambient temperature.
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System
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データ表示
SDS-PAGE

Biotinylated Human IL-6 R alpha, Avitag,His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
SEC-MALS

The purity of Biotinylated Human IL-6 R alpha, Avitag,His Tag (Cat. No. CD6-H82E8) is more than 85% and the molecular weight of this protein is around 65-80 kDa verified by SEC-MALS.
Report
Bioactivity-ELISA

Immobilized Human IL-6, premium grade (Cat. No. IL6-H4218) at 5 μg/mL (100 μL/well) can bind Biotinylated Human IL-6 R alpha, Avitag,His Tag (Cat. No. CD6-H82E8) with a linear range of 4-63 ng/mL (QC tested).
Protocol
Bioactivity-BLI

Loaded Biotinylated Human IL-6 R alpha, Avitag,His Tag (Cat. No. CD6-H82E8) on SA Biosensor, can bind Human IL-6, premium grade (Cat. No. IL6-H4218) with an affinity constant of 73.1 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).
Protocol
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最新の進展
- 英語名:
Interleukin-6 receptor alpha subunit
- カテゴリ:
- 市販の医薬品数:
8 詳細
- 治験医薬品数:
9 詳細
- 最新の開発ステージ:
Approved
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