Biotinylated Human IL-9 Protein, His,Avitag™ (MALS verified)

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製品番号/仕様
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数量
IL9-H82E3-25ug
$360.00
IL9-H82E3-200ug
$1565.00
ETA of in-stock products:2 business days
総アイテム数 製品金額$ 0

製品詳細

  • Synonyms

    Interleukin-9, IL-9, Cytokine P40

  • Source

    Biotinylated Human IL-9 Protein, His,Avitag (IL9-H82E3) is expressed from human 293 cells (HEK293). It contains AA Gln 19 - Ile 144 (Accession # P15248).

    Predicted N-terminus: Gln 19

    Request for sequence
  • Molecular Characterization

    IL-9 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).

    The protein has a calculated MW of 17.7 kDa. The protein migrates as 32-42 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Labeling

    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

  • Protein Ratio

    Passed as determined by the HABA assay / binding ELISA.

  • Purity

    >95% as determined by SDS-PAGE.

    >95% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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データ表示

  • SDS-PAGE

    IL-9 SDS-PAGE

    Biotinylated Human IL-9 Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    IL-9 SEC-MALS

    The purity of Biotinylated Human IL-9 Protein, His,Avitag (Cat. No. IL9-H82E3) is more than 95% and the molecular weight of this protein is around 25-32 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     IL-9 ELISA

    Immobilized Biotinylated Human IL-9 Protein, His,Avitag (Cat. No. IL9-H82E3) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Human IL-9R, Fc Tag (Cat. No. ILR-H5251) with a linear range of 0.2-10 ng/mL (QC tested).

    Protocol

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バックグランド

Interleukin-9 (IL-9) is expressed primarily by activated T cells. The growth factor and anti apoptotic activities of IL-9 on multiple transformed cells suggest a potential role for the cytokine in tumourigenesis. IL-9 has also been proposed as a candidate gene for asthma. IL-9 is a Th2-derived cytokine that has been reported to regulate T and B cell function. IL-9 was first isolated as a factor capable of sustaining the long-term growth of murine T cell clones, but has since been demonstrated to have in vitro activities on mast cells, erythroid progenitors, and B cell Ig expression.

最新の進展

 
医薬品開発の進捗
  • 英語名:

    Interleukin-9

  • カテゴリ:

  • 市販の医薬品数:

    0 詳細

  • 治験医薬品数:

    1 詳細

  • 最新の開発ステージ:

    Phase 2 Clinical

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