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ALK-7

ALK-7 Product List

Product Category
Protein (5)Cell (1)
Product Status
Launched (6)
Species
Human (4)Mouse (1)Rhesus macaque (1)
Tag
His Tag (3)Fc Tag & Avi Tag (1)- (1)Fc Tag (1)
Conjugate
Unconjugated (4)Biotin-labeled (1)- (1)

Cat. No.	Species	Host	Product Description
AL7-H5253	Human	HEK293	Human ALK-7 Protein, Fc Tag (MALS verified)
AL7-H52H5	Human	HEK293	Human ALK-7 Protein, His Tag (MALS verified)
AL7-H82F3	Human	HEK293	Biotinylated Human ALK-7 Protein, Fc,Avitag™ (MALS verified)
CHEK-ATF273	Human	HEK293	Human ALK-7 (Activin E receptor) (Luc) HEK293 Reporter Cell
AL7-M52H3	Mouse	HEK293	Mouse ALK-7 Protein, His Tag (HPLC verified)
AL7-R52H3	Rhesus macaque	HEK293	Rhesus macaque ALK-7 Protein, His Tag (MALS verified)

Total: 6

ALK-7 Background

ALK-7, also known as ACVR1C , is a Type I receptor for the TGF-beta family of signaling molecules. Upon ligand binding, it initiates intracellular signaling by phosphorylating cytoplasmic SMAD transcription factors. These activated SMADs then translocate to the nucleus to regulate gene expression, either directly or in complex with other transcription factors.