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Beta-NGF

Beta-NGF 詳細

英語名	Nerve growth factor	市販薬剤の数	0
治験薬の数	14	ターゲットの別称	Nerve Growth Factor
研究＆開発段階	NDA/BLA

英語名	Nerve growth factor
ターゲットの別称	Nerve Growth Factor
市販薬剤の数	0
治験薬の数	14
研究＆開発段階	NDA/BLA

Beta-NGF 製品リスト

属性
Protein (2)
製品ライブラリ
オンライン (2)
種
Human (1)Mouse (1)
タグ
Tag Free (2)
マーカー
Unconjugated (2)

製品番号	種	発現システム	製品説明	タンパク質の構造	純度	特性
BEF-H5214	Human	HEK293	Human Beta-NGF Protein, premium grade
BEF-M5213	Mouse	HEK293	Mouse Beta-NGF Protein, Tag Free, low endotoxin (MALS verified)

総数量2

Beta-NGFバックグランド

Nerve growth factor beta (beta-NGF) is a neurotrophic factor that plays critical role in the development and maintenance of sensory and sympathetic neurons. The active form of human beta-NGF is is a noncovalently disulfide-linked homodimer, which is secreted and signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways.

Beta-NGF分子の別称

NGF,NGFB,Beta-NGF,HSAN5,MGC161426,MGC161428

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
RGN-259	RGN-457; RGN-352; RGN-259; RGN-137; Tβ4; TB4; GBT-101; GBT-201; Thymosin beta 4-16-38; TB4 16-38; Thymosin beta4; Thymosin B4; Fx peptide	Phase 3 Clinical	National Institutes Of Health	Diabetes Mellitus; Dry Eye Syndromes; Epidermolysis Bullosa; Epidermolysis Bullosa Dystrophica; Epidermolysis Bullosa, Junctional; Graft vs Host Disease; Keratitis; Myocardial Infarction; Myocardial Ischemia; Pressure Ulcer; Sjogren's Syndrome; ST Elevation Myocardial Infarction; Varicose Ulcer; Xerophthalmia	詳細
Fasinumab	SAR-164877; MT-5547; R-475; REGN-475	Phase 3 Clinical	Regeneron Pharmaceuticals Inc	Abdominal Pain; Back Pain; Low Back Pain; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Sciatica	詳細
SSS-40	SSS-40; SSS-40-anti-NGF Ab; SSS40 anti-NGF Ab	Phase 2 Clinical	3sbio Inc	Bone Neoplasms; Cancer Pain; Osteoarthritis	詳細
SHR-2017	SHR-2017; SHR2017	Phase 2 Clinical	Suzhou Suncadia Biopharmaceuticals Co Ltd	Bone metastases; Multiple Myeloma; Osteoporosis; Solid tumours	詳細
Antibodies to humanized nerve growth factor(Shenyang Sunshine Pharmaceutical)		Phase 2 Clinical	Shenyang Sunshine Pharmaceutical Co Ltd	Bone metastases; Cancer Pain	詳細
EP-9001A	EP-9001A	Phase 2 Clinical	Chengdu Youluo Biotechnology Co Ltd	Bone metastases; Cancer Pain; Pain	詳細
DS-002	DS-002	Phase 2 Clinical	Dartsbio Pharmaceuticals Ltd	Cancer Pain; Pain	詳細
Atinumab	NG-101; ATI-355	Phase 2 Clinical	Novartis Pharma Ag	Diabetic Gastroparesis; Gastroparesis; Spinal Cord Injuries	詳細
Luvagrobart	AK-115	Phase 1 Clinical		Cancer Pain; Pain	詳細
4B03-04	4B03-04	Phase 1 Clinical	Fubei Biomedical Technology (Beijing) Co Ltd	Osteoarthritis	詳細
DS-010	DS010; DS-010	Phase 1 Clinical	Dartsbio Pharmaceuticals Ltd	Cachexia	詳細
TNM-009	TNM-009; TNM009	Phase 1 Clinical	Zhuhai Trinomab Pharmaceutical Co Ltd	Cancer Pain; Pain	詳細
SMR-7694	SMR-7694; SMR7694	Phase 1 Clinical	Sinobioway Biomedicine Co Ltd	Osteoarthritis	詳細
Neuroregenerative agents (iNtRON Biotechnology)		Clinical	Intron Biotechnology	Nervous System Diseases	詳細