Cadherin-3 詳細
Molecule Name
Cadherin 3
分子の別称
CDH3,CDHP,Cadherin-3,P-cadherin
Drug Development Progress
治験薬の数7
市販薬剤の数0
研究＆開発段階Phase 2 Clinical
ターゲットの別称
Cadherin 3， Type 1， P-Cadherin (Placental)，Placental Cadherin，CDHP，P-cadherin，CDH3，Cadherin 3，Calcium-Dependent Adhesion Protein， Placental，Cadherin 3， P-Cadherin (Placental)，Cadherin-3，HJMD，PCAD
バックグランド
Cadherin-3 （also known as P-cadherin）is a classical cell-to-cell adhesion molecule with a homeostatic function in several normal tissues. In humans, cadherin-3 is only detected in a few organs. However, its overexpression is strongly associated with a poor prognosis in some solid tumors including breast, lung and pancreatic cancers.
Cadherin-3 製品リスト
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治験薬に関する情報
| 英語名 | 研究コード | 研究開発ステージ | 会社 | 適応症 | 臨床試験 |
|---|---|---|---|---|---|
| STEMVAC | EP-101 | Phase 2 Clinical | Epithany | Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; HR-positive breast cancer; Lung Neoplasms; Triple Negative Breast Neoplasms | 詳細 |
| BC-3195 | BC3195; BC-3195 | Phase 2 Clinical | Wuxi BioCity | Neoplasm Metastasis; Neoplasms; Solid tumours | 詳細 |
| FF-21101-Y-90 | FF-21101-Y-90; PPMX-T002 | Phase 1 Clinical | Fujifilm Holdings Corp | Solid tumours | 詳細 |
| FF-21101 | FF-21101 | Phase 1 Clinical | Perseus Proteomics Inc | Bile Duct Neoplasms; Colorectal Neoplasms; Head and Neck Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Solid tumours | 詳細 |
| TRAILR2/CDH3 bispecific antibody (Boehringer Ingelheim) | Phase 1 Clinical | Boehringer Ingelheim International Gmbh | Neoplasms | 詳細 | |
| AMG 305 | AMG 305; AMG-305 | Phase 1 Clinical | Amgen Inc | Solid tumours | 詳細 |
| FF-21101In | FF-21101In | Phase 1 Clinical | PeptiDream Inc | Solid tumours | 詳細 |