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CD117

CD117 詳細

英語名	Stem cell growth factor receptor	市販薬剤の数	17
治験薬の数	37	ターゲットの別称	EC 2.7.10，EC:2.7.10.1，MASTC，KIT Proto-Oncogene Receptor Tyrosine Kinase，V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene-Like Protein，p145 c-kit，SCFR，KIT，Proto-Oncogene C-Kit，Proto-Oncogene Tyrosine-Protein Kinase Kit，Soluble KIT Variant 1，C-Kit Protooncogene，CD117 Antigen，Piebald Trait，EC 2.7.10.1，C-Kit，CD117，Proto-Oncogene Proteins c-kit，Mast/stem cell growth factor receptor Kit，PBT，Piebald trait protein，Tyrosine-protein kinase Kit，KIT Proto-Oncogene， Receptor Tyrosine Kinase，v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
研究＆開発段階	Approved

英語名	Stem cell growth factor receptor
ターゲットの別称	EC 2.7.10，EC:2.7.10.1，MASTC，KIT Proto-Oncogene Receptor Tyrosine Kinase，V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene-Like Protein，p145 c-kit，SCFR，KIT，Proto-Oncogene C-Kit，Proto-Oncogene Tyrosine-Protein Kinase Kit，Soluble KIT Variant 1，C-Kit Protooncogene，CD117 Antigen，Piebald Trait，EC 2.7.10.1，C-Kit，CD117，Proto-Oncogene Proteins c-kit，Mast/stem cell growth factor receptor Kit，PBT，Piebald trait protein，Tyrosine-protein kinase Kit，KIT Proto-Oncogene， Receptor Tyrosine Kinase，v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
市販薬剤の数	17
治験薬の数	37
研究＆開発段階	Approved

CD117 製品リスト

属性
Protein (15)
製品ライブラリ
オンライン (15)
種
Human (6)Mouse (2)Rhesus macaque (1)Cynomolgus (3)Canis (1)White-tufted-ear marmoset (1)Guinea pig (1)
タグ
His Tag (8)Fc Tag (4)His Tag & Avi Tag (3)
マーカー
Unconjugated (10)Biotin-labeled (3)APC Labeled (1)PE Labeled (1)

製品番号	種	発現システム	製品説明
HOT CD7-H5255	Human	HEK293	Human CD117 / c-kit Protein, Fc Tag, low endotoxin (MALS verified)
HOT CD7-H52H4	Human	HEK293	Human CD117 / c-kit Protein, His Tag, low endotoxin (MALS verified)
HOT CD7-H82E6	Human	HEK293	Biotinylated Human CD117 / c-kit Protein, His,Avitag™ (MALS verified)
HOT CD7-M5259	Mouse	HEK293	Mouse CD117 / c-kit Protein, Fc Tag (MALS verified)
HOT CD7-C52H9	Cynomolgus	HEK293	Cynomolgus CD117 / c-kit Protein, His Tag, low endotoxin (MALS verified)
CD7-H525b	Human	HEK293	Human CD117 / c-kit Protein, Fc Tag (MALS verified)
CD7-HA2H7	Human	HEK293	APC-Labeled Human CD117 Protein, His Tag
CD7-HP2H9	Human	HEK293	PE-Labeled Human CD117 Protein, His Tag
CD7-M82E3	Mouse	HEK293	Biotinylated Mouse CD117 / c-kit Protein, His,Avitag™ (MALS verified)
CD7-C52H3	Canis	HEK293	Canis CD117 / c-kit Protein, His Tag (MALS verified)

総数量15

CD117バックグランド

Mast/stem cell growth factor receptor Kit (c-Kit), a member of the protein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily, is also known as piebald trait protein (PBT), p145 c-kit, tyrosine-protein kinase Kit and CD117,which contains five Ig-like C2-type (immunoglobulin-like) domains and one protein kinase domain. CD117 acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, CD117 can activate several signaling pathways. Furthermore, Activated KIT promotes phosphorylation of the protein phosphatases PTPN6/SHP-1 and PTPRU, and of the transcription factors STAT1, STAT3, STAT5A and STAT5B.

CD117分子の別称

CD117,SCFR,c-Kit,KIT

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Barzolvolimab	CDX-0159	Phase 3 Clinical	University Of Toronto - St. George Campus, Yale University	Chronic Urticaria; Dermatitis, Atopic; Eosinophilic Esophagitis; Prurigo Nodularis; Skin Diseases; Symptomatic Dermographism; Urticaria	詳細
Seralutinib	PK-10571; GB-002	Phase 3 Clinical	Gilead Sciences Inc	Pulmonary Arterial Hypertension	詳細
Chiauranib	CS-2164; CS2164	Phase 3 Clinical	Shenzhen Chipscreen Biosciences Co Ltd	Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Lymphoma, Non-Hodgkin; Neoplasms; Ovarian Neoplasms; Sarcoma; Small Cell Lung Carcinoma; Solid tumours; Triple Negative Breast Neoplasms	詳細
Bezuclastinib	PLX-9486; CGT-9486	Phase 3 Clinical	Daiichi Sankyo Co Ltd	Gastrointestinal Stromal Tumors; Hematologic Neoplasms; Leukemia, Mast-Cell; Mastocytosis; Mastocytosis, Systemic; Neoplasm Metastasis	詳細
oral enteric coated imatinib (Tenax Therapeutics)	TNX-201 (Tenax Therapeutics)	Phase 3 Clinical	PH Precision Med	Pulmonary Arterial Hypertension	詳細
Sitravatinib	MG-516; MG-91516; MGCD-516; IND-155305; MGCD-0516	Phase 3 Clinical	Mirati Therapeutics Inc	Biliary Tract Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Endometrial Neoplasms; Esophageal Squamous Cell Carcinoma; Gastrointestinal Neoplasms; Hepatic Insufficiency; Kidney Neoplasms; Liposarcoma; Lung Diseases; Lung Neoplasms; Metastatic breast cancer; Neoplasms; Oral Squamous Cell Carcinoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms; Ureteral Neoplasms; Uterine Cervical Neoplasms; Uveal melanoma	詳細
AZD-3229	NB-003; NB003; AZD-3229; AZD3229	Phase 3 Clinical	Astrazeneca Turkey	Gastrointestinal Stromal Tumors; Influenza B virus infection; Solid tumours	詳細
Elenestinib	BLU-263	Phase 3 Clinical	Blueprint Medicines Corp	Mastocytosis, Systemic	詳細
Autologous Human C-Kit Cardiac Stem Cells (CSCs) II (ISCI / University of Miami Miller School of Medicine)		Phase 2 Clinical	Elpiscience (Shanghai) Biopharma Ltd, University Of Miami	Myocardial Infarction; Ventricular Dysfunction, Left	詳細
Telatinib	EOC-315; BAY-57-9352	Phase 2 Clinical	Bayer AG	Solid tumours; Stomach Neoplasms	詳細
Briquilimab	AMG-191; JSP-191; JSP191	Phase 2 Clinical	Amgen Inc, National Heart, Lung And Blood Institute, Stanford University	Anemia, Sickle Cell; Asthma; Chronic Urticaria; Granulomatous Disease, Chronic; Immunologic Deficiency Syndromes; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Severe Combined Immunodeficiency	詳細
BLU-808	SAR-449028; BLU-808	Phase 2 Clinical	Blueprint Medicines Corp	Chronic Urticaria; Conjunctivitis, Allergic	詳細
DCC-3009	DCC-3009	Phase 2 Clinical	Deciphera Pharmaceuticals Inc	Gastrointestinal Stromal Tumors	詳細
Sorafenib Tosylate/Comekibart	MG-D-1609	Phase 2 Clinical	Metagone Biotech Inc	Solid tumours	詳細
Opelkibart elmanitin	MGTA-117	Phase 2 Clinical	Heidelberg Pharma AG	Leukemia, Myeloid, Acute; Myelodysplastic Syndromes	詳細
Hydroxychloroquine/Sorafenib		Phase 2 Clinical	Vg Life Sciences	Ovarian Neoplasms; Solid tumours	詳細
18F-Dasatinib	18F-SKI-249380; [18F]-Fluoro-BMS-354825; [18F]Dasatinib; [18F]SKI-249380; [18F]Fluoro-BMS-354825	Phase 1 Clinical	Memorial Sloan Kettering Cancer Center	Bone Marrow Neoplasms; Carcinoma; Diagnostic agents; Lymphoma; Melanoma; Neoplasms; Sarcoma	詳細
anti-CD117 CAR-T cells (Poseida Therapeutics)		Phase 1 Clinical	Poseida Therapeutics Inc	Hematopoietic stem cell transplantation (HSCT); Leukemia, Myeloid, Acute	詳細
Tafetinib Malate	SIM-0702; SIM-1005; SIM-010603	Phase 1 Clinical	Jiangsu Simcere Pharmaceutical Co Ltd, Jilin Boda Pharmaceutical Co Ltd, Nanjing Yoko Biomedical Co Ltd	Neoplasms	詳細
BEAM-103	BEAM-103	Phase 1 Clinical	Beam Therapeutics Inc	Anemia, Sickle Cell; beta-Thalassemia	詳細
DPH-001	DPH-001; DPH001	Phase 1 Clinical	Disruptive Pharma AB		詳細
ALY-301	ALY-301; GTX-B001	Phase 1 Clinical	Alys Pharmaceuticals Inc	Chronic Urticaria; Symptomatic Dermographism; Urticaria	詳細
QBH-196	QBH-196	Phase 1 Clinical	Shenyang Pharmaceutical University	Solid tumours; Stomach Neoplasms	詳細
ETN-101	ETN101; ETN-101; MBP-11901	Phase 1 Clinical	Etnova Therapeutics Corp	Carcinoma, Hepatocellular; Liver Neoplasms	詳細
CSCJC-3456	CSCJC3456; CSCJC-3456	Phase 1 Clinical	Changshan ConjuChem BioPharmaceutical Research and Development (Hebei) Co Ltd, Hebei Changshan Biochemical Pharmaceutical Co Ltd	Solid tumours	詳細
THB-335	THB-335; THB335	Phase 1 Clinical	Third Harmonic Bio	Inflammation	詳細
ND-003 (NewDEL Biotech)	ND003 (NewDEL Biotech); ND-003 (NewDEL Biotech); ND003; JND-5932	Phase 1 Clinical	Jinan University, Shenzhen NewDEL Biotech Co Ltd	Dermatitis, Atopic; Gastrointestinal Stromal Tumors; Idiopathic Pulmonary Fibrosis; Neoplasms; Pulmonary Fibrosis; Renal fibrosis; Renal Insufficiency, Chronic; Solid tumours	詳細
CDX-622	CDX-622	Phase 1 Clinical	Celldex Therapeutics Inc	Asthma; Fibrosis; Hypersensitivity; Inflammation	詳細
QX-013N	QX-013-N; QX013N	Phase 1 Clinical	Qyuns Therapeutics Co Ltd	Chronic Urticaria; Urticaria	詳細
NN-2101	NN-2101	Phase 1 Clinical	Novelty Nobility Inc	Diabetic macular oedema; Diabetic Retinopathy; Retinal Diseases; Retinal Vein Occlusion; Wet Macular Degeneration	詳細
NN-3201	NN-3201	Phase 1 Clinical	Novelty Nobility Inc	Carcinoma, Adenoid Cystic; Carcinoma, Renal Cell; Gastrointestinal Stromal Tumors; Leukemia, Myeloid, Acute; Neuroendocrine Tumors; Small Cell Lung Carcinoma; Uveal melanoma	詳細
THB-001	THB-001	Phase 1 Clinical	Novartis Corp	Chronic Urticaria; Gastrointestinal Diseases; Respiratory Tract Diseases	詳細
T-1301	T-1301; DBPR-216; BPR-1J481; BPR1J481	Phase 1 Clinical	Taivex Therapeutics Corp	Lymphoma; Solid tumours	詳細
GS-0174	GS-0174	Phase 1 Clinical	Forty Seven Inc	Hematologic Neoplasms	詳細
TR-64	TR-64	Phase 1 Clinical	Tarapeutics Science Inc	Gastrointestinal Stromal Tumors; Solid tumours	詳細
AGX-0073	AGX-0073	Phase 1 Clinical	Shanghai Aojian Biological Technology Co Ltd	Solid tumours	詳細
Sorafenib tosylate (Bio-Synectics)	BS-104	Clinical	Bio-Synectics Inc		詳細

市販薬剤に関する情報

英語名	研究コード	研究開発ステージ	会社	オリジナル製品名	最初に承認をした国	最初の適応症	最初に承認を受けた会社	承認された日付	適応症	臨床試験
Anlotinib Dihydrochloride	AL-3818	Approved	Advenchen Laboratories Llc, Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd	福可维	Mainland China	Carcinoma, Non-Small-Cell Lung	Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd	2018-05-08	Bile Duct Diseases; Bone Neoplasms; Breast Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Ovarian Epithelial; Carcinoma, Renal Cell; Colorectal Neoplasms; Craniopharyngioma; Endometrial Neoplasms; Esophageal Squamous Cell Carcinoma; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Gastroenteropancreatic neuroendocrine tumor; Gastroesophageal Junction Neoplasms; Gastrointestinal Stromal Tumors; Glioma; Head and Neck Neoplasms; Hepatic Insufficiency; Leiomyosarcoma; Liver Dysfunction; Lung Diseases, Interstitial; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Medullary thyroid cancer (MTC); Melanoma; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasms; Neuroendocrine Tumors; Osteoma; Ovarian Neoplasms; Peritoneal Neoplasms; Sarcoma; Sarcoma, Alveolar Soft Part; Sarcoma, Synovial; Small Cell Lung Carcinoma; Solid tumours; Stomach Neoplasms; Thoracic Neoplasms; Thyroid Neoplasms; Urologic Neoplasms; Uterine Cervical Neoplasms	詳細
Imatinib mesylate	CGP-57148B; CGP-57148; STI-571; QTI-571; CTI-571; VR325; AER-901; YD-312; TNX-201	Approved	Novartis Pharma Ag	glivic, 格列卫, Gleevec, Ruvise, Glivec, Gleevec/Glivec	EU	Leukemia, Myelogenous, Chronic	Novartis Europharm Ltd	2001-05-10	Abdominal Neoplasms; Acute Lung Injury; Amyloidosis; Anemia, Sickle Cell; Angioimmunoblastic T-cell Lymphoma; Asthma; Brain Neoplasms; Breast Neoplasms; Breast Neoplasms, Male; Burkitt Lymphoma; Carcinoma, Adenoid Cystic; Carcinoma, Neuroendocrine; Carcinoma, Ovarian Epithelial; Central Nervous System Lymphoma; Chordoma; Chronic eosinophilic leukemia (CEL); CNS Embryonal Tumor; Colonic Neoplasms; Colorectal Neoplasms; Congenital Bone Marrow Failure Syndromes; Coronavirus Disease 2019 (COVID-19); Dermatofibrosarcoma; Desmoplastic Small Round Cell Tumor; Diabetes Mellitus, Type 1; Diabetic macular oedema; Dry Socket; Eosinophilia; Fallopian Tube Neoplasms; Fibroma; Fibrosarcoma; Gastrointestinal Stromal Tumors; Genital Diseases, Male; Genital Neoplasms, Male; Glioblastoma; Glioma; Graft vs Host Disease; Head and Neck Neoplasms; Hemangiopericytoma; Hematologic Neoplasms; Hematopoietic stem cell transplantation (HSCT); Histiocytoma, Malignant Fibrous; Hodgkin Disease; Hypereosinophilic Syndrome; Hypertension, Pul	詳細
Lenvatinib Mesilate	E-7080; MK-7902; ER-203492-00	Approved	Eisai Co Ltd	Kisplyx, Lenvima, Lenvima/Kisplyx, 乐卫玛	United States	Thyroid Neoplasms	Eisai Inc	2015-02-13	Adenocarcinoma; Adenocarcinoma of Lung; Adenocarcinoma, Follicular; Biliary Tract Neoplasms; Breast Neoplasms; Carcinoma, Adenoid Cystic; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Cholangiocarcinoma; Endometrial Neoplasms; Esophageal Neoplasms; Gastrointestinal Stromal Tumors; Glioma; Hepatic Insufficiency; Liver Diseases; Liver Neoplasms; Lymphoma; Melanoma; Neoplasm Metastasis; Neoplasms; Neuroendocrine Tumors; Osteosarcoma; Ovarian Neoplasms; Paraganglioma; Pheochromocytoma; Renal Insufficiency; Solid tumours; Stomach Neoplasms; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Uterine Cervical Neoplasms	詳細
Regorafenib	DAST; BAY-73-4506	Approved	Bayer AG	Stivarga, Resihance	United States	Colorectal Neoplasms	Bayer Healthcare Pharmaceuticals Inc	2012-09-27	Adenocarcinoma; Adenoma; Bile Duct Neoplasms; Carcinoma, Adenoid Cystic; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Ovarian Epithelial; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Colonic Neoplasms; Colorectal Neoplasms; Esophageal adenocarcinoma; Esophageal Neoplasms; Fallopian Tube Neoplasms; Gastrinoma; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Glucagonoma; Hemangiosarcoma; Insulinoma; Leukemia, Myeloid, Acute; Liver Neoplasms; Lung Neoplasms; Melanoma; Meningioma; Neoplasm Metastasis; Neoplasms; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Rectal Neoplasms; Sarcoma; Sarcoma, Ewing; Solid tumours; Somatostatinoma; Stomach Neoplasms; Thymoma; Thyroid Neoplasms	詳細
Avapritinib	BLU-285; CS-3007	Approved	Blueprint Medicines Corp	Ayvakit, Ayvakyt, 泰吉华, Taijihua	United States	Gastrointestinal Stromal Tumors	Blueprint Medicines Corp	2020-01-09	Adenocarcinoma; Breast Neoplasms; Central Nervous System Neoplasms; Colorectal Neoplasms; Esophageal Neoplasms; Gastrointestinal Stromal Tumors; Hematologic Neoplasms; Leukemia, Mast-Cell; Lung Neoplasms; Mastocytosis, Systemic; Melanoma; Sarcoma; Solid tumours; Stomach Neoplasms	詳細
Vorolanib	CM-082; X-82; EYP-1901; XV-615	Approved	Tyrogenex Inc	伏美纳, DURAVYU™	Mainland China	Carcinoma, Renal Cell	Betta Pharmaceuticals Co Ltd	2023-06-07	Adenocarcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Choroidal Neovascularization; Diabetic macular oedema; Diabetic Retinopathy; Eye Diseases; Gastroesophageal Junction Neoplasms; Kidney Neoplasms; Leukemia, Myeloid, Acute; Macular Degeneration; Melanoma; Neoplasms; Pancreatic Neoplasms; Retinal Degeneration; Retinal Diseases; Small Cell Lung Carcinoma; Solid tumours; Stomach Neoplasms; Wet Macular Degeneration	詳細
Ripretinib	DCC-2618	Approved	Deciphera Pharmaceuticals	Qinlock, 擎乐	United States	Gastrointestinal Stromal Tumors	Deciphera Pharmaceuticals Llc	2020-05-15	Gastrointestinal Stromal Tumors; Mastocytosis, Systemic; Neoplasms	詳細
Olverembatinib	D-824; GZD-824; APG-1351; GIBH-824; HQP-1351	Approved	Guangzhou Institute Of Biomedicine And Health, Chinese Academy Of Sciences	耐立克	Mainland China	Leukemia, Myelogenous, Chronic; Leukemia, Myeloid, Accelerated Phase	Guangzhou Shunjian Biomedical Technology Co Ltd	2021-11-25	Gastrointestinal Stromal Tumors; Hepatic Insufficiency; Leukemia, Lymphoid; Leukemia, Myelogenous, Chronic; Leukemia, Myeloid; Leukemia, Myeloid, Accelerated Phase; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Solid tumours	詳細
Ponatinib Hydrochloride	AP24534 hydrochloride; AP24534-HCL; AP24534 HCl; INCB-84344; AP-24534	Approved	Ariad	英可欣, Iclusig	United States	Leukemia, Myelogenous, Chronic; Precursor Cell Lymphoblastic Leukemia-Lymphoma	Ariad Pharmaceuticals Inc	2012-12-14	Adenocarcinoma of Lung; Blast Crisis; Carcinoma, Non-Small-Cell Lung; Common Bile Duct Neoplasms; Gastrointestinal Stromal Tumors; Glioblastoma; Head and Neck Neoplasms; Hematologic Neoplasms; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Myelogenous, Chronic; Leukemia, Myeloid, Accelerated Phase; Leukemia, Myeloid, Acute; Leukemia, Myeloid, Chronic-Phase; Leukemia, Myelomonocytic, Chronic; Lymphoma; Medullary thyroid cancer (MTC); Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Small Cell Lung Carcinoma; Solid tumours; Thyroid Neoplasms	詳細
Sunitinib Malate	PNU-290940AD; PHA-290940AD; SCAI-003; SU-010398; SU-11248; GB-102; PHA-290940; PNU-290940; SU-011248-L-malate salt	Approved	Pfizer Inc	Sutent, 索坦	United States	Gastrointestinal Stromal Tumors; Carcinoma, Renal Cell	Cppi Cv	2006-01-26	Abdominal Neoplasms; Adenocarcinoma; Adenocarcinoma, Follicular; Adenoma, Islet Cell; Adrenocortical Carcinoma; AIDS-Related Complex; Amyloidosis; Angioimmunoblastic T-cell Lymphoma; Astrocytoma; Barrett Esophagus; Brain metastases; Brain Neoplasms; Breast Neoplasms; Burkitt Lymphoma; Carcinoma; Carcinoma, Acinar Cell; Carcinoma, Adenoid Cystic; Carcinoma, Adenosquamous; Carcinoma, Embryonal; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Ovarian Epithelial; Carcinoma, Papillary; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Central Nervous System Neoplasms; Choriocarcinoma; Chronic eosinophilic leukemia (CEL); Cognition Disorders; Colorectal Neoplasms; Diabetic macular oedema; Endodermal Sinus Tumor; Endometrial Neoplasms; Ependymoma; Esophageal Neoplasms; Fallopian Tube Neoplasms; Fibromatosis, Aggressive; Fibrosarcoma; Gastrointestinal Stromal Tumors; Germinoma; Glioblastoma; Glioma; Gliosarcoma; Head and Neck Neoplasms; Hemangi	詳細
Dasatinib Hydrate	NSC-732517; BMS-354825	Approved	Bristol-Myers Squibb Company	Spraysel, 施达赛, Spricel, Sprycel	United States	Precursor Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Myelogenous, Chronic	Bristol-Myers Squibb Company	2006-06-28	Adenocarcinoma, Clear Cell; Angioimmunoblastic T-cell Lymphoma; Astrocytoma; Blast Crisis; Bone metastases; Brain Neoplasms; Breast Neoplasms; Burkitt Lymphoma; Carcinoma, Basosquamous; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Carcinoma, Verrucous; Cholangiocarcinoma; Chondrosarcoma; Chordoma; Colonic Neoplasms; Coronavirus Disease 2019 (COVID-19); Cystadenocarcinoma; Endometrial Neoplasms; Fallopian Tube Neoplasms; Gastrointestinal Stromal Tumors; Giant Cell Tumor of Bone; Glioblastoma; Glioma; Gliosarcoma; Heart Arrest; Hemangiopericytoma; Hematologic Neoplasms; HIV Infections; Hodgkin Disease; Hormone-Resistant Prostate Neoplasms; Hypereosinophilic Syndrome; Hypopharyngeal Neoplasms; Idiopathic Pulmonary Fibrosis; Immunoproliferative Small Intestinal Disease; Intraocular Lymphoma; Laryngeal Diseases; Laryngeal Neoplasms; Leukemia; Leukemia, Hairy Cell; Leukemia, Large Granular Lymphocytic; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Leukemia, Myel	詳細
Pexidartinib	PLX-3397	Approved	Daiichi Sankyo Co Ltd	Turalio	United States	Giant Cell Tumor of Tendon Sheath	Daiichi Sankyo Inc	2019-08-02	Arthritis, Rheumatoid; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Giant Cell Tumor of Tendon Sheath; Giant Cell Tumors; Glioblastoma; Hodgkin Disease; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Melanoma; Metastatic breast cancer; Neoplasm Metastasis; Neoplasms; Neurofibroma, Plexiform; Neurofibrosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Sarcoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Synovitis, Pigmented Villonodular	詳細
Pazopanib Hydrochloride	GSK-786034; GW-786034B; SB-786034; GW-786034	Approved	Glaxosmithkline Plc, Novartis Pharma Ag	维全特, Armala, Votrient, Patorma	United States	Carcinoma, Renal Cell; Sarcoma	Novartis Pharma Ag	2009-10-19	Adenocarcinoma, Follicular; Brain Neoplasms; Breast Neoplasms; Breast Neoplasms, Male; Carcinoma, Embryonal; Carcinoma, Hepatocellular; Carcinoma, Neuroendocrine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Ovarian Epithelial; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Central Nervous System Neoplasms; Chondrosarcoma; Chondrosarcoma, Extraskeletal Myxoid; Choriocarcinoma; Colorectal Neoplasms; Dermatofibrosarcoma; Endodermal Sinus Tumor; Epistaxis; Fallopian Tube Neoplasms; Fibromatosis, Aggressive; Gastrinoma; Gastroenteropancreatic neuroendocrine tumor; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Genital Neoplasms, Female; Germinoma; Glioblastoma; Glioma; Gliosarcoma; Glucagonoma; Hemangiosarcoma; Herpes Genitalis; Herpes Simplex; HIV Infections; Hormone-Resistant Prostate Neoplasms; Insulinoma; Leiomyosarcoma; Leukemia, Myeloid, Acute; Liposarcoma; Lung Neoplasms; Lymphoma; Macular Degeneration; Medullary thyroid cancer (MTC); Melanoma; Mesothelioma; Multiple Endocrine Neoplasia T	詳細
Cabozantinib S-malate	XL-184; BMS-907351; RO7047650; RO-7047650	Approved	Exelixis Inc	Cometriq, Cabometyx	United States	Thyroid Neoplasms; Carcinoma, Neuroendocrine	Exelixis Inc	2012-11-29	Adenocarcinoma, Clear Cell; Adenocarcinoma, Follicular; Adenoma, Islet Cell; Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Astrocytoma; Bile Duct Neoplasms; Bone metastases; Brain metastases; Brain Neoplasms; Breast Neoplasms; Carcinoma, Adenosquamous; Carcinoma, Endometrioid; Carcinoma, Hepatocellular; Carcinoma, Merkel Cell; Carcinoma, Neuroendocrine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Ovarian Epithelial; Carcinoma, Papillary; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Central Nervous System Neoplasms; Cholangiocarcinoma; Colorectal Neoplasms; Endometrial Neoplasms; Fallopian Tube Neoplasms; Gastroenteropancreatic neuroendocrine tumor; Glioblastoma; Glioma; Gliosarcoma; Hepatic Insufficiency; Hepatoblastoma; HIV Infections; Kidney Neoplasms; Leiomyosarcoma; Leukemia, Myeloid, Acute; Lymphoma; Medullary thyroid cancer (MTC); Melanoma; Meningioma; Multiple Myeloma; Neoplasm Metastasis; Neoplasms; Neoplasms, Germ Cell and Embryonal; Neuroblastoma; Neuroendocrin	詳細
Sorafenib Tosylate	NSC-724772; BAY-43-0006; BAY-43-9006; BAY-54-9085	Approved	Onyx Pharmaceuticals Inc	Nexavar, 多吉美	United States	Carcinoma, Renal Cell	Bayer Healthcare Pharmaceuticals Inc	2005-12-01	Abdominal Neoplasms; Adenocarcinoma; Angioimmunoblastic T-cell Lymphoma; Astrocytoma; Bile Duct Neoplasms; Brain Neoplasms; Breast Neoplasms; Breast Neoplasms, Male; Burkitt Lymphoma; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Ovarian Epithelial; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Carcinoma, Verrucous; Cholangiocarcinoma; Colonic Neoplasms; Esophageal Neoplasms; Facial Neoplasms; Fallopian Tube Neoplasms; Fibromatosis, Aggressive; Gallbladder Neoplasms; Gastrinoma; Gastroesophageal Junction Neoplasms; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Glioblastoma; Gliosarcoma; Glucagonoma; Head and Neck Neoplasms; Heart Arrest; Hemangiosarcoma; Hepatopulmonary Syndrome; Histiocytoma, Malignant Fibrous; Hypertension, Portal; Hypopharyngeal Neoplasms; Insulinoma; Kidney Diseases; Kidney Neoplasms; Laryngeal Diseases; Laryngeal Neoplasms; Leiomyosarcoma; Leukemia, Basophilic, Acute; Leukemia, Eosin	詳細
Famitinib Malate	SHR-1020	Approved	Jiangsu Hengrui Medicine Co Ltd	艾比特	Mainland China	Uterine Cervical Neoplasms	Jiangsu Hengrui Medicine Co Ltd	2025-05-27	Adenocarcinoma; Biliary Tract Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Cholangiocarcinoma; Colorectal Neoplasms; Endometrial Neoplasms; Gastroenteropancreatic neuroendocrine tumor; Gastrointestinal Stromal Tumors; Genital Neoplasms, Female; Idiopathic Pulmonary Fibrosis; Lung Neoplasms; Metastatic breast cancer; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasms; Ovarian Neoplasms; Pancreatic neuroendocrine tumors (pNET); Small Cell Lung Carcinoma; Solid tumours; Thyroid Neoplasms; Triple Negative Breast Neoplasms; Urologic Neoplasms; Uterine Cervical Neoplasms	詳細
Midostaurin	PKC-412; PKC-412A; CGP-41231; CGP-41251	Approved	Novartis Pharma Ag	Rydapt	United States	Hematologic Neoplasms; Leukemia, Myeloid, Acute; Mastocytosis, Systemic; Leukemia, Mast-Cell	Novartis Pharmaceuticals Corp	2017-04-28	Hematologic Neoplasms; Hepatic Insufficiency; Leukemia; Leukemia, Mast-Cell; Leukemia, Myeloid, Acute; Mastocytosis; Mastocytosis, Systemic; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma	詳細

レビュー

V***l2022-06-25
0評価
Human CD117 / c-kit Protein, His Tag, low endotoxin (MALS verified)
We used the c-Kit protein to immunizations projects we are carrying for our studies and they performed great. The delivery was also very fast and the purchasing process very easy. We also purchased several other antibodies and recombinant proteins that we are currently testing and they all have very good quality. I have not used directly the technical services because it was not necessary, as the website is very easy and informative, so I found the products we wanted with no problem.