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CEACAM-5

CEACAM-5 詳細

英語名	Carcinoembryonic antigen related cell adhesion molecule 5	市販薬剤の数	0
治験薬の数	18	ターゲットの別称	CEA Cell Adhesion Molecule 5，CEACAM5，Meconium antigen 100，CEA，Carcinoembryonic Antigen Related Cell Adhesion Molecule 5，Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5，Carcinoembryonic Antigen，CD66e Antigen，CD66e
研究＆開発段階	Phase 3 Clinical

英語名	Carcinoembryonic antigen related cell adhesion molecule 5
ターゲットの別称	CEA Cell Adhesion Molecule 5，CEACAM5，Meconium antigen 100，CEA，Carcinoembryonic Antigen Related Cell Adhesion Molecule 5，Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5，Carcinoembryonic Antigen，CD66e Antigen，CD66e
市販薬剤の数	0
治験薬の数	18
研究＆開発段階	Phase 3 Clinical

CEACAM-5 製品リスト

属性
Protein (18)Cell (2)Cell Grade Beads (1)Beads (1)
製品ライブラリ
オンライン (22)
種
Human (16)Mouse (2)Cynomolgus (3)Rhesus macaque (1)
タグ
His Tag (8)His Tag & Avi Tag (4)Fc Tag (3)Fc Tag & Avi Tag (1)Llama IgG Fc Tag (2)- (4)
マーカー
Unconjugated (11)Biotin-labeled (5)FITC Labeled (2)- (4)

製品番号	種	発現システム	製品説明
HOT CE5-H5226	Human	HEK293	Human CEACAM-5 / CD66e Protein, His Tag (MALS verified)
HOT CE5-H82E0	Human	HEK293	Biotinylated Human CEACAM-5 / CD66e Protein, His,Avitag™ (MALS verified)
HOT CE5-C52H5	Cynomolgus	HEK293	Cynomolgus CEACAM-5 / CD66e Protein, His Tag, low endotoxin (MALS verified)
CE5-H5253	Human	HEK293	Human CEACAM-5 Protein, Fc Tag (HPLC verified)
CE5-H5259	Human	HEK293	Human CEACAM-5 Protein, Llama IgG2b Fc Tag, low endotoxin (MALS verified)
CE5-H52H3	Human	HEK293	Human CEACAM-5 / CD66e (145-322) Protein, His Tag (MALS verified)
CE5-H52H4	Human	HEK293	Human CEACAM-5 / CD66e (323-500) Protein, His Tag (MALS verified)
CE5-H52H8	Human	HEK293	Human CEACAM-5 / CD66e (499-685) Protein, His Tag, low endotoxin (MALS verified)
CE5-H82E3	Human	HEK293	Biotinylated Human CEACAM-5 / CD66e (499-685) Protein, His,Avitag™ (MALS verified)
CE5-H82E4	Human	HEK293	Biotinylated Human CEACAM-5 / CD66e (593-675) Protein, His,Avitag™ (MALS verified)

総数量22

CEACAM-5バックグランド

Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) is also Carcinoembryonic antigen (CEA), Meconium antigen 100, CD antigen CD66e, CEACAM5 belongs to the immunoglobulin superfamily and CEA family. CEACAM5 contains seven Ig-like (immunoglobulin-like) domains. CEACAM5 is homodimer protein which binding of E.coli Dr adhesins leads to dissociation of the homodimer. CEACAM5 is cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. CEACAM5 is receptor for E.coli Dr adhesins.

CEACAM-5分子の別称

CEACAM-5,CD66e,CEA,Meconium antigen 100

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Tusamitamab Ravtansine	SAR-408701; IBI-126	Phase 3 Clinical	Immunogen Inc	Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Esophageal Neoplasms; Lung Neoplasms; Metastatic breast cancer; Neoplasms; Pancreatic Neoplasms; Stomach Neoplasms	詳細
SGM-101	SGM-101	Phase 3 Clinical	Surgimab Sas	Brain Diseases; Brain metastases; Brain Neoplasms; Colonic Diseases; Colonic Neoplasms; Colorectal Neoplasms; Gastrointestinal Diseases; Gastrointestinal Neoplasms; Intestinal Diseases; Intestinal Neoplasms; Pancreatic Neoplasms; Rectal Neoplasms	詳細
Cancer vaccine (BN ImmunoTherapeutics/National Cancer Institute)	CVAC-301; CV-301	Phase 2 Clinical	Therion Biologics	Adenocarcinoma; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Colorectal Neoplasms; Cystadenocarcinoma; Intestinal Neoplasms; Melanoma; Neoplasm Metastasis; Ovarian Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Solid tumours; Urinary Bladder Neoplasms	詳細
NEO-201	NEO-201	Phase 2 Clinical	National Cancer Institute, Precision Biologics Inc	Carcinoma, Non-Small-Cell Lung; Squamous Cell Carcinoma of Head and Neck; Uterine Cervical Neoplasms; Uterine Neoplasms	詳細
Anti-CEA CAR T cell therapy (Shanghai GeneChem)		Phase 2 Clinical	Shanghai Genechem Co Ltd	Colorectal Neoplasms; Liver Neoplasms	詳細
BMS-986490	BMS-986490	Phase 2 Clinical	Bristol-Myers Squibb Company	Solid tumours	詳細
LM-24C5	LM-24C5	Phase 2 Clinical	LaNova Medicines Ltd	Neoplasms; Solid tumours	詳細
Precemtabart tocentecan	M-9140; M9140	Phase 2 Clinical	Merck KGaA, Darmstadt, Germany	Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Colorectal Neoplasms; Pancreatic Neoplasms; Solid tumours; Stomach Neoplasms	詳細
MFE-23-CD3z T cell therapy (Cancer Research Technology)		Phase 1 Clinical	Cancer Research Technology	Neoplasms	詳細
anti-CEA CAR T-cell therapy (Shanghai First Song Therapeutics)		Phase 1 Clinical	Shanghai Simcere Pharmaceutical Co Ltd	Colorectal Neoplasms; Esophageal Neoplasms; Pancreatic Neoplasms; Small Intestine Cancers; Solid tumours; Stomach Neoplasms	詳細
125-Iodine-labeled MFE-23		Phase 1 Clinical	Cancer Research UK	Neoplasms	詳細
anti-CEA CAR-T cell therapy (Sorrento/TNK therapeutics/Roger Williams Medical Center)		Phase 1 Clinical	Beth Israel Deaconess Medical Center	Adenocarcinoma; Liver Neoplasms; Neoplasm Metastasis; Neoplasms; Pancreatic Neoplasms; Solid tumours	詳細
CEACAM5-TOPO1 ADC (Bristol-Myers Squibb Company)		Phase 1 Clinical	Bristol-Myers Squibb Company	Solid tumours	詳細
124I-M5A		Phase 1 Clinical	City Of Hope National Medical Center, National Cancer Institute	Colorectal Neoplasms	詳細
IBI-3020	IBI3020; IBI-3020	Phase 1 Clinical	Xinda Biomedical Technology (Hangzhou) Co Ltd	Neoplasm Metastasis; Solid tumours	詳細
SGN-CEACAM5C	PF-08046050; SGN-CEACAM5C; SAR445953; SAR-445953	Phase 1 Clinical	Sanofi, Seagen Inc	Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Colorectal Neoplasms; Gastroesophageal Junction Neoplasms; Small Cell Lung Carcinoma; Solid tumours; Stomach Neoplasms	詳細
EBC-129	EBC129; EBC-129	Phase 1 Clinical	Experimental Drug Development Centre	Solid tumours	詳細
GB-5012	GB-5012	Clinical	Shanghai Genbase Biotechnology Co Ltd	Colonic Neoplasms	詳細