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GSK-3beta

GSK-3beta 詳細

英語名	Glycogen synthase kinase-3 beta	市販薬剤の数	0
治験薬の数	4	ターゲットの別称	EC 2.7.11，EC:2.7.11.26，EC:2.7.11.1，Serine/threonine-protein kinase GSK3B，Glycogen synthase kinase-3 beta，GSK3B，Glycogen Synthase Kinase 3 Beta，GSK-3 Beta，GSK3beta Isoform，EC 2.7.11.26，EC 2.7.11.1
研究＆開発段階	Phase 3 Clinical

英語名	Glycogen synthase kinase-3 beta
ターゲットの別称	EC 2.7.11，EC:2.7.11.26，EC:2.7.11.1，Serine/threonine-protein kinase GSK3B，Glycogen synthase kinase-3 beta，GSK3B，Glycogen Synthase Kinase 3 Beta，GSK-3 Beta，GSK3beta Isoform，EC 2.7.11.26，EC 2.7.11.1
市販薬剤の数	0
治験薬の数	4
研究＆開発段階	Phase 3 Clinical

GSK-3beta 製品リスト

属性
Protein (1)
製品ライブラリ
オンライン (1)
種
Human (1)
タグ
His Tag (1)
マーカー
Unconjugated (1)

製品番号	種	発現システム	製品説明	タンパク質の構造	純度	特性
GSB-H5545	Human	InsectCells	Human GSK-3beta / GSK-3β Protein, His Tag (active enzyme, MALS verified)

総数量1

GSK-3betaバックグランド

Glycogen synthase kinase-3 (GSK-3) is a pivotal molecule in the development of Alzheimer's disease (AD). GSK-3beta is involved in the formation of paired helical filament (PHF)-tau, which is an integral component of the neurofibrillary tangle (NFT) deposits that disrupt neuronal function, and a marker of neurodegeneration in AD.

GSK-3beta分子の別称

GSK3B,Glycogen synthase kinase-3 beta

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Tideglusib	NP-12; AMO-02; NP-031112	Phase 3 Clinical	Noscira Sa	Alzheimer Disease; Amyotrophic Lateral Sclerosis; Autism Spectrum Disorder; Cardiomyopathies; Myotonic Dystrophy	詳細
Ruboxistaurin Mesilate Hydrate	LY-333531; REC 3599; SM 030	Phase 2 Clinical	Eli Lilly And Company	Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic macular oedema; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Gangliosidoses, GM2; Heart Failure; Hyperpigmentation; Melanosis	詳細
Elraglusib	9-ING-41	Phase 2 Clinical	Actuate Therapeutics Inc, Northwest University, University Of Illinois At Chicago	Adenocarcinoma; Bone metastases; Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Carcinoma, Adenoid Cystic; Colorectal Neoplasms; Dermatofibrosarcoma; Diffuse Intrinsic Pontine Glioma; Glioma; Hemangiosarcoma; Kidney Neoplasms; Leiomyosarcoma; Leukemia-Lymphoma, Adult T-Cell; Liposarcoma; Lung Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Meningioma; Neoplasm Metastasis; Neoplasms; Neuroblastoma; Osteosarcoma; Pancreatic Neoplasms; Primary Myelofibrosis; Rhabdomyosarcoma; Salivary Gland Neoplasms; Sarcoma; Sarcoma, Ewing; Sarcoma, Synovial	詳細
Asnuciclib	CDKI-73; LS-007; QHRD-107	Phase 2 Clinical	Shandong University, University Of South Australia	Leukemia, Myeloid, Acute	詳細