IFN-gamma

IFN-gamma

IFN-gamma 詳細

Molecule Name
Interferon gamma
分子の別称
Interferon-gamma ,Interferon-γ
Drug Development Progress
治験薬の数13
市販薬剤の数4
研究&開発段階Approved
ターゲットの別称
Immune interferon,Interferon gamma,IFNG,IFN-Gamma,IFG,IFI,Interferon-gamma
バックグランド
Interferon-gamma (IFN-γ/IFNG) is a dimerized soluble cytokine that is the only member of the type II class of interferon. This interferon was originally called macrophage-activating factor, a term now used to describe a larger family of proteins to which IFN-γ belongs. IFN-gamma has been used in a wide variety of clinical indications. Interferon-gamma (IFNgamma) is a central regulator of the immune response and signals via the Janus Activated Kinase (JAK)-Signal Transducer and Activator of Transcription (STAT) pathway. Interferon gamma has broader roles in activation of innate and adaptive immune responses to viruses and tumors, in part through upregulating transcription of genes involved in cell cycle regulation, apoptosis, and antigen processing/presentation. Despite this, rodent and human trophoblast cells show dampened responses to IFNG that reflect the resistance of these cells to IFNG-mediated activation of major histocompatibility complex (MHC) class II transplantation antigen expression.

IFN-gamma 製品リスト

Species
  • Human(3)
  • Mouse(2)
Tag
  • Tag Free(3)
  • His Tag(1)
  • His Tag & Avi Tag(1)
Host
  • HEK293(5)
Conjugate
  • Unconjugated(4)
  • Biotin-labeled(1)
Grade
  • RUO(3)
  • GMP(1)
  • PG (pre-GMP)(1)
Low Endotoxin
  • No(5)
MoleculeCat. No.Product Name種HostStructurePurityActivitySize&Price
IFN-gamma
Human IFN-gamma / IFNG Protein, premium grade
Human
HEK293
MALSSDS-PAGE
ELISACELL BASE

$80.00

20ug
IFN-gamma
GMP Human IFN-gamma Protein
Human
HEK293
SDS-PAGE
CELL BASE

$235.00

50ug
IFN-gamma
Human IFN-gamma / IFNG Protein, Research Grade
Human
HEK293
MALSSDS-PAGE
ELISACELL BASE

$59.00

20ug
IFN-gamma
Mouse IFN-gamma / IFNG Protein, His Tag (MALS verified)
Mouse
HEK293
MALSSDS-PAGE
ELISA

$290.00

100ug
IFN-gamma
Avitag
IFG-M82E3
Biotinylated Mouse IFN-gamma Protein, His,Avitag™ (MALS verified)
Mouse
HEK293
MALSSDS-PAGE
ELISA

$315.00

25ug
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治験薬に関する情報

英語名研究コード研究開発ステージ会社適応症臨床試験
PDS-0101PDS-0101B; PDS-0101C; PDS-0101; PDS-0101A; PDS-101Phase 3 ClinicalPds Biotechnology Corp
Anus Neoplasms; Carcinoma, Squamous Cell; Head and Neck Neoplasms; HIV Infections; Oropharyngeal Neoplasms; Papillomavirus Infections; Uterine Cervical Neoplasms; Vulvar Neoplasms
詳細
Tadekinig alfar-hIL-18BP; IL-18BPPhase 3 ClinicalAb2 Bio Ltd
Autoimmune Lymphoproliferative Syndrome; Lymphohistiocytosis, Hemophagocytic; Macrophage Activation Syndrome
詳細
SFA-002SFA-002; SFA002Phase 3 ClinicalSFA Therapeutics Inc
Arthritis, Rheumatoid; Plaque psoriasis; Psoriasis
詳細
IMNN-001GEN-1; EGEN-001; IMNN-001; phIL-12-005/PPCPhase 3 ClinicalExpression Genetics
Carcinoma, Endometrioid; Carcinoma, Ovarian Epithelial; Colorectal Neoplasms; Cystadenocarcinoma; Cystadenocarcinoma, Serous; Fallopian Tube Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms
詳細
TAX-2TAX-2; AP-01; AP-02Phase 2 ClinicalCentre National De La Recherche Scientifique (Cnrs), University of Reims
Solid tumours; Thrombosis
詳細
OCH-NCNP1OCH-NCNP1Phase 2 ClinicalKeio University
Crohn Disease; Multiple Sclerosis
詳細
KIO-101PP-001; KIO-101; KIO-104Phase 2 Clinical4sc Ag
Conjunctival Diseases; Dry Eye Syndromes; Eye Diseases; Keratoconjunctivitis; Uveitis; Xerophthalmia
詳細
ASN-002 (Ascend Biopharmaceuticals)TG-1042; Ad-IFNγ; SP-002 (Ascend Biopharmaceuticals)Phase 2 ClinicalTransgene Sa
Basal Cell Nevus Syndrome; Carcinoma, Basal Cell; Lymphoma, B-Cell; Skin Melanoma; Skin Neoplasms; Solid tumours
詳細
IndemakitugEI-001Phase 2 ClinicalElixiron Immunotherapeutics Inc
Vitiligo
詳細
IFN-gamma-secreting HAdV antigen specific T cells (Case Comprehensive Cancer Center)Phase 1 ClinicalCase Comprehensive Cancer Center
Hematopoietic stem cell transplantation (HSCT)
詳細
Recombinant human interferon gamma adenovirus injection (Guangzhou Dabo Biological Products)Phase 1 ClinicalGuangzhou Dabo Biological Products Co Ltd
Liver Neoplasms; Nasopharyngeal Neoplasms; Prostatic Neoplasms, Castration-Resistant
詳細
TAGX-0003TAGX-0003; CGB-600Phase 1 ClinicalTagCyx Biotechnologies
Alopecia Areata; Autoimmune Diseases; Cystitis, Interstitial; Skin Diseases; Vitiligo
詳細
[89Zr]Zr-DFO-emapalumab[89Zr]Zr-DFO-emapalumabPhase 1 ClinicalBarbara Ann Karmanos Cancer Institute
Carcinoma, Non-Small-Cell Lung
詳細

市販薬剤に関する情報

英語名研究コード研究開発ステージ会社オリジナル製品名最初に承認をした国最初の適応症最初に承認を受けた会社承認された日付適応症臨床試験
Cadi-05Cadi-05ApprovedNational Institute Of Allergy And Infectious Diseases (Niaid)Immuvac, Leprovac, Mycidac-CIndiaLeprosy; Carcinoma, Non-Small-Cell Lungnull1998-01-01
Carcinoma, Non-Small-Cell Lung; Leprosy; Squamous Cell Carcinoma of Head and Neck
詳細
PropagermaniumSK-818; SK-818CApprovedSanwa Kagaku Kenkyusho Co LtdSerocionJapanHepatitis BSanwa Kagaku Kenkyusho Co Ltd1994-01-01
Hepatitis B
詳細
EmapalumabNI-0501ApprovedNovimmune SaGamifantUnited StatesLymphohistiocytosis, HemophagocyticNovimmune Sa2018-11-20
Arthritis, Juvenile; Cytopenia; Dermatomyositis; Hematopoietic stem cell transplantation (HSCT); Immune System Diseases; Lung Diseases, Interstitial; Lupus Erythematosus, Systemic; Lymphohistiocytosis, Hemophagocytic; Macrophage Activation Syndrome; Polyendocrinopathies, Autoimmune; Rare Diseases; Sepsis; Still's Disease, Adult-Onset
詳細
ThalidomideNSC-66847; NSC-527179; K-17; FPF-300; FPF300ApprovedCelgene CorpTalizer, Thalidomide Celgene, Thalidomide Pharmion, Synovir, Thalomid, ThaledMainland ChinaLeprosy, Lepromatous; Multiple MyelomaChangzhou Pharmaceutical Factory1982-01-01
Acquired Immunodeficiency Syndrome; Adenocarcinoma, Clear Cell; Adenoma, Islet Cell; Amyotrophic Lateral Sclerosis; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Anemia, Sideroblastic; Angiodysplasia; Appendiceal Neoplasms; Arachnoiditis; Arteriovenous Malformations; Axial Spondyloarthritis; beta-Thalassemia; Burning Mouth Syndrome; Carcinoid Tumor; Carcinoma, Adenosquamous; Carcinoma, Hepatocellular; Cholangitis, Sclerosing; Colorectal Neoplasms; Cough; Endometrial Neoplasms; Endometriosis; Epilepsy; Erythema Nodosum; Gastric Antral Vascular Ectasia; Gastrointestinal Hemorrhage; Genetic Diseases, Inborn; Glioma; Graft vs Host Disease; Head and Neck Neoplasms; Hemoglobinopathies; HIV Infections; HIV Wasting Syndrome; Hodgkin Disease; Hormone-Resistant Prostate Neoplasms; Hypertension, Portal; Idiopathic Pulmonary Fibrosis; Kidney Neoplasms; Leiomyosarcoma; Leprosy, Lepromatous; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelomonocytic, Chronic; Liver Neoplasms; Lung Neoplasms
詳細
Customer Reviews
  • M***r2025-10-31
    Reliable and easy-to-use ELISA kit with high sensitivity and consistent results. Standards and controls performed as expected, and the shorter assay time is a great advantage for our studies.