IL-31 RA

IL-31 RA 詳細

英語名Interleukin-31 receptor subunit alpha市販薬剤の数1
治験薬の数0ターゲットの別称GLM-R,CRL,IL-31R subunit alpha,IL-31 receptor subunit alpha,Cytokine receptor-like 3,Gp130-like monocyte receptor,IL-31RA,ZcytoR17,IL-31R-alpha,PRO21384,GPL,CRL3,GLMR,Interleukin 31 Receptor A,Soluble Type I Cytokine Receptor CRL3,PLCA2,Class I Cytokine Receptor,hGLM-R,Gp130-like receptor
研究&開発段階Approved
英語名Interleukin-31 receptor subunit alpha
ターゲットの別称GLM-R,CRL,IL-31R subunit alpha,IL-31 receptor subunit alpha,Cytokine receptor-like 3,Gp130-like monocyte receptor,IL-31RA,ZcytoR17,IL-31R-alpha,PRO21384,GPL,CRL3,GLMR,Interleukin 31 Receptor A,Soluble Type I Cytokine Receptor CRL3,PLCA2,Class I Cytokine Receptor,hGLM-R,Gp130-like receptor
市販薬剤の数1
治験薬の数0
研究&開発段階Approved

IL-31 RA 製品リスト

  • 属性

    Protein (6)

  • 製品ライブラリ

    オンライン (6)

  • 種

    Human (4)Cynomolgus (1)Mouse (1)

  • タグ

    Fc Tag (3)His Tag (1)His Tag & Avi Tag (1)Fc Tag & Avi Tag (1)

  • マーカー

    Unconjugated (4)Biotin-labeled (2)

IL-31 RAバックグランド

Interleukin-31 receptor subunit alpha is a protein that in humans is encoded by the IL31RA gene, also known as IL-31 receptor subunit alpha, IL-31RA, GLM-R, Gp130-like receptor, CRL3, GPL. Oncostatin M receptor (OSMR) and IL31RA form the heterodimeric receptor through which IL31 signals. IL31RA is a strong activator of STAT3 and STAT5, whereas STAT1 is only marginally tyrosine-phosphorylated. dditionally, demonstrate Jak1 binding to GPL and its activation in heteromeric complexes with the OSMRbeta but also in a homomeric receptor complex.

IL-31 RA分子の別称

IL-31 RA,IL-31RA,hGLM-R,CRL3,GPL,ZcytoR17,GLM-R,IL-31R-alpha,Gp130-like receptor

市販薬剤に関する情報

英語名研究コード研究開発ステージ会社オリジナル製品名最初に承認をした国最初の適応症最初に承認を受けた会社承認された日付適応症臨床試験
NemolizumabCD-14152; CIM-331; M 5250; M 5250BApprovedChugai Pharmaceutical Co LtdMitchga, NemluvioJapanDermatitis, Atopic; PruritusMaruho Co Ltd2022-03-28Dermatitis, Atopic; Prurigo; Prurigo Nodularis; Pruritus; Scleroderma, Systemic
詳細
  • 製品リスト
  • 市販薬剤に関する情報