KIR2DL3 詳細
Molecule Name
Killer cell immunoglobulin-like receptor 2DL3
分子の別称
CD158b2
Drug Development Progress
治験薬の数1
市販薬剤の数0
研究＆開発段階Phase 2 Clinical
ターゲットの別称
P58.2 MHC Class-I Specific NK Receptor，MHC Class I NK Cell Receptor，CD158b2 Antigen，KIR-K7b，KIR-K7c，KIR2DS5，CD158b，KIR2DL，NKAT2A，NKAT2B，GL183，NKAT，P58，Receptors， KIR2DL3，Cl-6，Killer Cell Immunoglobulin-Like Receptor Two Domains Long Cytoplasmic Tail 3，Natural Killer Cell Inhibitory Receptor KIR2DL3，Natural Killer Associated Transcript 2，p58.2 MHC class-I-specific NK receptor，Natural killer-associated transcript 2，NKAT-2，NKAT2，p58 natural killer cell receptor clone CL-6，Killer inhibitory receptor cl 2-3，CD158b2，Killer cell immunoglobulin-like receptor 2DL3，KIR2DL3，Killer Cell Immunoglobulin Like Receptor， Two Ig Domains And Long Cytoplasmic Tail 3，CD158 Antigen-Like Family Member B2，P58 NK Receptor CL-6，KIR-023GB，KIRCL23，Killer Cell Immunoglobulin-Like Receptor， Two Domains， Short Cytoplasmic Tail， 5，Killer Cell Immunoglobulin-Like Receptor， Two Domains， Long Cytoplasmic Tail， 3
バックグランド
Killer cell immunoglobulin-like receptor 2DL3 (KIR2DL3) is also known as CD158 antigen-like family member B2, KIR-023GB, Killer inhibitory receptor cl 2-3, MHC class I NK cell receptor, NKAT2a, NKAT2b, Natural killer-associated transcript 2, p58 natural killer cell receptor clone CL-6, p58.2 MHC class-I-specific NK receptor, CD158b2 and KIR2DL3, which is a single-pass type I membrane protein and belongs to the immunoglobulin superfamily.KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). KIR2DL3 can inhibit the activity of NK cells thus preventing cell lysis.
KIR2DL3 製品リスト
You Have Viewed 0 Of 0 Results
治験薬に関する情報
| 英語名 | 研究コード | 研究開発ステージ | 会社 | 適応症 | 臨床試験 |
|---|---|---|---|---|---|
| Lirilumab | IPH-21; NN-1975; IPH-2101; IPH-2102; BMS-986015 | Phase 2 Clinical | Novo Nordisk A/S | Bone Marrow Neoplasms; Hodgkin Disease; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Multiple Myeloma; Neoplasms; Smoldering Multiple Myeloma; Squamous Cell Carcinoma of Head and Neck; Urinary Bladder Neoplasms | 詳細 |