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LTBR

LTBR 詳細

英語名	Tumor necrosis factor receptor superfamily member 3	市販薬剤の数	0
治験薬の数	1	ターゲットの別称	Lymphotoxin-beta receptor，Tumor necrosis factor receptor type III，LTBR，Tumor necrosis factor receptor superfamily member 3，D12S370，TNFRSF3，TNFCR，TNFR3，TNFR Superfamily， Member 3，Lymphotoxin B Receptor，LT-BETA-R，TNF-R-III，TNFR2-RP，TNF-RIII，TNFR-III，TNFR-RP，Lymphotoxin beta Receptor，Tumor necrosis factor C receptor，Tumor Necrosis Factor Receptor 2-Related Protein，Lymphotoxin Beta Receptor (TNFR Superfamily， Member 3)
研究＆開発段階	Phase 1 Clinical

英語名	Tumor necrosis factor receptor superfamily member 3
ターゲットの別称	Lymphotoxin-beta receptor，Tumor necrosis factor receptor type III，LTBR，Tumor necrosis factor receptor superfamily member 3，D12S370，TNFRSF3，TNFCR，TNFR3，TNFR Superfamily， Member 3，Lymphotoxin B Receptor，LT-BETA-R，TNF-R-III，TNFR2-RP，TNF-RIII，TNFR-III，TNFR-RP，Lymphotoxin beta Receptor，Tumor necrosis factor C receptor，Tumor Necrosis Factor Receptor 2-Related Protein，Lymphotoxin Beta Receptor (TNFR Superfamily， Member 3)
市販薬剤の数	0
治験薬の数	1
研究＆開発段階	Phase 1 Clinical

LTBR 製品リスト

属性
Protein (5)
製品ライブラリ
オンライン (5)
種
Human (3)Cynomolgus (1)Mouse (1)
タグ
His Tag & Avi Tag (2)Fc Tag (1)His Tag (2)
マーカー
Biotin-labeled (1)Unconjugated (4)

製品番号	種	発現システム	製品説明
HOT LTR-H5259	Human	HEK293	Human LTBR / TNFRSF3 Protein, Fc Tag (MALS verified)
HOT LTR-H52E3	Human	HEK293	Unconjugated Human LTBR / TNFRSF3 Protein, His,Avitag™ (MALS verified)
HOT LTR-H82E9	Human	HEK293	Biotinylated Human LTBR / TNFRSF3 Protein, His,Avitag™ (MALS verified)
LTR-M52H3	Mouse	HEK293	Mouse LTBR / TNFRSF3 Protein, His Tag (MALS verified)
LTR-C52H3	Cynomolgus	HEK293	Cynomolgus LTBR / TNFRSF3 Protein, His Tag

総数量5

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LTBRバックグランド

Lymphotoxin-beta receptor (LTBR) is also known as Tumor necrosis factor receptor superfamily member 3 (TNFRSF3), Tumor necrosis factor receptor type III (TNF-RIII), which is a single-pass type I membrane protein containing four TNFR-Cys repeat regions. Except for interacting with HCV core protein, LTBR can not only associate with itself, but also can associate with TRAF3, TRAF4 and TRAF5. As the receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT, LTBR promotes apoptosis via TRAF3 and TRAF5. Furthermore, LTBR may play a role in the development of lymphoid organs.