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MRGPRX2

MRGPRX2 製品リスト

属性
Cell (3)Protein (4)
製品ライブラリ
オンライン (6)研究中 (1)
種
Human (7)
タグ
- (6)Flag Tag & Avi Tag (1)
マーカー
- (3)Unconjugated (2)Biotin-labeled (1)FITC Labeled (1)

製品番号	種	発現システム	製品説明
CHEK-ATF300	Human	HEK293	Human MRGPRX2 (Luc) HEK293 Reporter Cell
CHEK-ATP214	Human	HEK293	HEK293/Human MRGPRX2 Stable Cell Line
MR2-H52D3	Human	HEK293	Human MRGPRX2 Full Length Protein, Flag Tag (Nanodisc-pro)
MR2-H52P3	Human	HEK293	Human MRGPRX2 Full Length Protein (VLP)
MR2-H82D5	Human	HEK293	Biotinylated Human MRGPRX2 Full Length Protein, Flag,Avitag™ (Nanodisc-pro)
MR2-HF2D3	Human	HEK293	FITC-Labeled Human MRGPRX2 Full Length Protein, Flag Tag (Nanodisc-pro)
SCCHO-ATP215	Human	CHO	CHO/Human MRGPRX2 Stable Cell Line

総数量7

MRGPRX2バックグランド

The protein belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. It is moderately expressed in undifferentiated HL60 cells, and is located on both chromosomes X and Y.

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Dronabinol(AXIM Biotechnologies)		Phase 3 Clinical	Axim Biotech	Neoplasms; Child Nutrition Disorders; Vomiting; Nausea; Cachexia; Sarcopenia; Anorexia Nervosa	詳細
Adezunap	AP-707	Phase 3 Clinical	CannaXan GmbH	Multiple Sclerosis; Accidental Injuries; Low Back Pain; Diabetes Mellitus; Peripheral Nerve Injuries; Diabetic peripheral neuropathy; Back Pain; Neuralgia; Somatoform Disorders; Stroke; Peripheral Nervous System Diseases; Brachial Plexus Neuropathies; Phantom Limb; Pain, Postoperative; Diabetic Neuropathies; Brain Injuries, Traumatic; Chronic Pain; Pain; Paraplegia	詳細
Dronabinol（Vertanical）	VER-01	Phase 3 Clinical	Vertanical GmbH	Low Back Pain	詳細
cannabidiol (Cardiol Therapeutics)		Phase 3 Clinical	Cardiol Therapeutics Inc	Coronavirus Disease 2019 (COVID-19); Pericarditis; Cardiovascular Diseases; Myocarditis	詳細
V-24343	V-24343; ANEB-001	Phase 2 Clinical	Vernalis Plc	Poisoning; Obesity	詳細
11C-MePPEP	11C-MePPEP	Phase 2 Clinical	Eli Lilly And Company	Substance-Related Disorders; Obesity	詳細
AX-1602	AX-1602	Phase 2 Clinical	Axim Biotech	Psoriasis; Dermatitis, Atopic; Vitiligo	詳細
Nimacimab	RYI-018; RYI-028; JNJ-2463	Phase 2 Clinical	Bird Rock Bio Inc	Metabolic Dysfunction-Associated Steatotic Liver Disease; Renal Insufficiency, Chronic; Obesity; Diabetic Gastroparesis	詳細
ART-2713	NEO-1940; ART-2713; ART27.13; AZD-1940	Phase 2 Clinical	Astrazeneca Plc, Neomed Inc, Pfizer Inc	Weight Loss; Pain; Anorexia; Cachexia; Low Back Pain	詳細
Cannabidiol/hydroxychloroquine	IHL-675A; IHL-675	Phase 2 Clinical	Incannex Healthcare Ltd	Arthritis, Rheumatoid; Respiratory Distress Syndrome, Adult	詳細
AEF-0217	AEF-0217	Phase 2 Clinical	Aelis Farma	Down Syndrome	詳細
Monlunabant	MRI-1891; NN9440–INV-202; INV-202	Phase 2 Clinical	Inversago Pharma Inc	Metabolic Syndrome; Metabolic Diseases; Diabetic Nephropathies; Obesity	詳細
IGC-AD1	IGC-AD1	Phase 2 Clinical	University Of South Florida	Anxiety; Depression; Alzheimer Disease; Psychomotor Agitation; Memory Disorders	詳細
AEF-0117	AEF-0117	Phase 2 Clinical	National Institute On Drug Abuse, Aelis Farma	Marijuana Abuse	詳細
[11C]OMAR	[11C]JHU-75528	Phase 1 Clinical	Johns Hopkins University School Of Medicine	Marijuana Abuse; Schizophrenia	詳細
ZYN-001	ZYN-001	Phase 1 Clinical	Zynerba Pharmaceuticals	Neuralgia; Fibromyalgia	詳細
Tetrahydrocannabivarin	GWP-42004; THCV; O-4394; DELTA9-THCV; GW-42004	Phase 1 Clinical	Gw Pharmaceuticals Plc	Diabetes Mellitus, Type 2; Hyperglycemia; Metabolic Syndrome; Obesity, Morbid; Hypercholesterolemia; Dyslipidemias	詳細
Zevaquenabant	MRI-1867; (S)-MRI-1867; INV-101	Phase 1 Clinical	National Institutes Of Health	Scleroderma, Systemic; Colitis, Ulcerative	詳細
TPT0301	TPT-0301; TPT0301	Phase 1 Clinical	Tetra Pharm Technologies ApS	Chronic Pain	詳細
INV-347	NN9441; NN-9441; INV-347	Phase 1 Clinical	Inversago Pharma Inc	Obesity	詳細
IPI 201（Isosceles Pharmaceuticals Inc ）	IPI-201	Phase 1 Clinical		Pain, Postoperative	詳細
GFB-024		Phase 1 Clinical	Takeda Pharma	Kidney Diseases; Endocrine System Diseases; Diabetic Nephropathies; Diabetes Complications; Diabetes Mellitus	詳細
DBPR-211		Phase 1 Clinical	National Health Research Institutes	Diabetes Mellitus, Type 2	詳細
MP-10X	MP-10X	Clinical	Medipure Holdings	Pain	詳細
Cannabidiol/Palmitoylethanolamide	THX-210; SCI–210	Clinical	Therapix Biosciences Ltd	Autism Spectrum Disorder; Diabetic Neuropathies	詳細
C20T5	C20T5		Murdoch Childrens Research Institute		詳細
C12T12	C12T12		Murdoch Childrens Research Institute		詳細

市販薬剤に関する情報

英語名	研究コード	研究開発ステージ	会社	オリジナル製品名	最初に承認をした国	最初の適応症	最初に承認を受けた会社	承認された日付	適応症	臨床試験
Cannabidiol/Dronabinol	THC-5; delta-9-THC/CBD; MPL-001; MPL-005; GW-1000; KL16-012; BOL-DP-o-04; GW-1000-02; PPP-001; MGC-ODT	Approved	Gw Pharmaceuticals	Sativex, Qixleef	Canada	Muscle Spasticity; Neuralgia; Cancer Pain; Chronic Pain; Multiple Sclerosis	null	2005-04-01	Back Pain; Phobia, Social; Neuralgia, Postherpetic; Huntington Disease; Reflex Sympathetic Dystrophy; Tourette Syndrome; Muscle Spasticity; Malnutrition; Sciatica; Acute Pain; Neuromyelitis Optica; Arthritis, Psoriatic; Neuralgia; Dementia; Panic Disorder; Osteoarthritis, Knee; Hepatic Insufficiency; Stress Disorders, Post-Traumatic; Healthy Aging; Hidradenitis Suppurativa; Agoraphobia; Drug Resistant Epilepsy; Renal Insufficiency, Chronic; Social Behavior; Corticobasal degeneration; Cerebral Palsy; Low Back Pain; Neoplasms; Sleep Initiation and Maintenance Disorders; Peripheral Nervous System Diseases; Pain; Chronic Pain; Depression; Depressive Disorder, Major; Marijuana Abuse; Marijuana Use; Spasm; Squamous Cell Carcinoma of Head and Neck; Cancer Pain; Renal Insufficiency; Spinal Cord Injuries; Migraine Disorders; Arthritis, Rheumatoid; Neck Pain; Diabetic Neuropathies; Sleep Wake Disorders; Opioid-Related Disorders; Essential Tremor; Anorexia; Anxiety Disorders; Kidney Diseases; Multiple Sclerosis; Tic Dis	詳細
Cannabidiol	AVCN-583601; GLA-015; BTX-1503; BTX-1801; BTX-1702; LYT-310; RAD011; PBX-1308; RAD-011; BRCX-014; RLS-103; GWP-42003; GWP-42003-P; BOL-DP-o-05; GW-42003; BTX-1204; ZYN-002; PTL-101; CHI-902; APH-1501	Approved	Gw Pharmaceuticals Plc	Epidiolex, Epidyolex, Zygel, Cannepil	United States	Epilepsies, Myoclonic; Lennox Gastaut Syndrome	null	2018-06-25	Migraine Disorders; Peripheral Nervous System Diseases; Acne Vulgaris; HIV Infections; Tobacco Smoking; Ovarian Neoplasms; Sleep Initiation and Maintenance Disorders; Facial Pain; Substance-Related Disorders; Marijuana Smoking; Tobacco Use Cessation; Anxiety; Pain; Chronic Pain; Marijuana Use; Seizures; Tuberous Sclerosis; Rett Syndrome; Schizophrenia; Appetitive Behavior; Autism Spectrum Disorder; Marijuana Abuse; Brain Injuries, Traumatic; Depression; Alcoholic Intoxication; Inflammatory Bowel Diseases; Fatty Liver; Child Behavior Disorders; Diabetes Mellitus, Type 2; Spinal Cord Injuries; Sleep Wake Disorders; Anxiety Disorders; Neoplasms; Opioid-Related Disorders; Diabetic Neuropathies; Coronavirus Disease 2019 (COVID-19); Musculoskeletal Pain; Graft vs Host Disease; Blepharospasm; Dyspepsia; Arthritis, Rheumatoid; Psychotic Disorders; Hyperalgesia; Chronic Urticaria; Hoarding Disorder; Bipolar Disorder; Pancreatic Neoplasms; Brain Diseases; Dysmenorrhea; Sturge-Weber Syndrome; Lennox Gastaut Syndrome; Ph	詳細