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PSCA

PSCA 詳細

英語名	Prostate stem cell antigen	市販薬剤の数	0
治験薬の数	4	ターゲットの別称	Prostate stem cell antigen，UNQ206/PRO232，PSCA，PRO232
研究＆開発段階	Phase 1 Clinical

英語名	Prostate stem cell antigen
ターゲットの別称	Prostate stem cell antigen，UNQ206/PRO232，PSCA，PRO232
市販薬剤の数	0
治験薬の数	4
研究＆開発段階	Phase 1 Clinical

PSCA 製品リスト

属性
Protein (5)
製品ライブラリ
オンライン (5)
種
Human (4)Mouse (1)
タグ
His Tag (3)His Tag & Avi Tag (2)
マーカー
Unconjugated (1)Biotin-labeled (2)PE Labeled (1)AF488 Labeled (1)

製品番号	種	発現システム	製品説明
HOT PSA-H52H6	Human	HEK293	Human PSCA Protein, His Tag
HOT PSA-H82E3	Human	HEK293	Biotinylated Human PSCA Protein, His,Avitag™ (MALS verified)
PSA-HA2H3	Human	HEK293	Alexa Fluor™ 488-Labeled Human PSCA Protein, His Tag (Site-specific conjugation)
PSA-HP2H3	Human	HEK293	PE-Labeled Human PSCA Protein, His Tag (Site-specific conjugation)
PSA-M82Ea	Mouse	HEK293	Biotinylated Mouse PSCA Protein, His,Avitag™, low endotoxin (MALS verified)

総数量5

PSCAバックグランド

The Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored protein, plays an important role in tumorigenesis. The prostate stem cell antigen (PSCA) gene, which encodes a prostate-specific antigen (PSA), was identified as a gene involved in cell adhesion and proliferation. PSCA may be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro. May act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits nicotine-induced signaling probably implicating alpha-3:beta-2- or alpha-7-containing nAChRs.

PSCA分子の別称

PSCA,UNQ206,PRO232

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Autologous Anti-PSCA-CAR-4-1BB/TCRzeta-CD19t-expressing T-lymphocytes (City of Hope Medical Center)		Phase 1 Clinical	City Of Hope National Medical Center	Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant	詳細
124-iodine-labeled PSCA targeting minibody (ImaginAb)		Phase 1 Clinical	University Of California At Los Angeles	Pancreatic Neoplasms; Prostatic Neoplasms; Urinary Bladder Neoplasms	詳細
anti-PSMA/anti-PSCA CAR T-cell therapy PD-1 silent (Shanghai Unicar-Therapy Bio-medicine)		Phase 1 Clinical	Shanghai Unicar-Therapy Bio-Medicine Technology Co Ltd	Hormone-Resistant Prostate Neoplasms	詳細
MB-104	MB-104; MB-105; MB-104 CS1 CAR; MB-105 PSCA CAR	Phase 1 Clinical	City Of Hope National Medical Center	Glioblastoma; Multiple Myeloma; Pancreatic Neoplasms; Prostatic Neoplasms; Stomach Neoplasms; Urinary Bladder Neoplasms	詳細