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SOD1

SOD1 詳細

英語名	Superoxide dismutase	市販薬剤の数	3
治験薬の数	13	ターゲットの別称	SOD1，Superoxide Dismutase 1，HSod1，Amyotrophic Lateral Sclerosis 1 (Adult)，Epididymis Secretory Protein Li 44，Superoxide Dismutase [Cu-Zn]，Cu/Zn Superoxide Dismutase，Indophenoloxidase A，SOD， Soluble，EC 1.15.1.1，HEL-S-44，IPOA，ALS1，SOD，ALS，Superoxide Dismutase，STAHP，EC:1.15.1.1，Superoxide Dismutase 1， Soluble，Superoxide Dismutase， Cystolic，Homodimer
研究＆開発段階	Approved

英語名	Superoxide dismutase
ターゲットの別称	SOD1，Superoxide Dismutase 1，HSod1，Amyotrophic Lateral Sclerosis 1 (Adult)，Epididymis Secretory Protein Li 44，Superoxide Dismutase [Cu-Zn]，Cu/Zn Superoxide Dismutase，Indophenoloxidase A，SOD， Soluble，EC 1.15.1.1，HEL-S-44，IPOA，ALS1，SOD，ALS，Superoxide Dismutase，STAHP，EC:1.15.1.1，Superoxide Dismutase 1， Soluble，Superoxide Dismutase， Cystolic，Homodimer
市販薬剤の数	3
治験薬の数	13
研究＆開発段階	Approved

SOD1 製品リスト

属性
Protein (2)
製品ライブラリ
オンライン (2)
種
Human (2)
タグ
His Tag (2)
マーカー
Unconjugated (2)

製品番号	種	発現システム	製品説明	タンパク質の構造	純度	特性
SO1-H5146	Human	E. coli	Human SOD1 / Cu-Zn SOD Pre-formed Fibrils Protein, His Tag
SO1-H5148	Human	E. coli	Human SOD1 / Cu-Zn SOD Protein, His Tag, low Endotoxin (active enzyme)

総数量2

お問い合わせ

SOD1バックグランド

Superoxide dismutase [Cu-Zn] (SOD1) is also known as superoxide dismutase 1 (hSod1), an enzyme that in humans is encoded by the SOD1 gene, located on chromosome 21. SOD1 can bind copper and zinc ions and is one of three superoxide dismutases responsible for destroying free superoxide radicals in the body. The encoded isozyme (SOD1) is a soluble cytoplasmic and mitochondrial intermembrane space protein, acting as a homodimer to convert naturally occurring, but harmful, superoxide radicals to molecular oxygen and hydrogen peroxide. Furthermore, the mutations of SOD1 gene can result in a neurodegenerative disorder affecting upper motor neurons in the brain and lower motor neurons in the brain stem and spinal cord.

SOD1分子の別称

SOD1,Superoxide dismutase 1,hSod1

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Otaplimastat	SP-8203 hydrochloride; SP8203 HCL; SP-8203	Phase 3 Clinical	Shin Poong Pharmaceutical Co Ltd	Ischemic Stroke	詳細
Bis-choline tetrathiomolybdate	ATN-224; WTX-101; ALXN-1840	Phase 2 Clinical	Wilson Therapeutics	Hepatolenticular Degeneration; Melanoma; Multiple Myeloma; Prostatic Neoplasms	詳細
Superoxide dismutase (Ube Industries)	r-hSOD; FKU-871	Phase 2 Clinical	Astellas Pharma Inc, Ube Industries Ltd	Diabetic Neuropathies; Myocardial Ischemia	詳細
BMX-010	BMX-010; MnTE-2-PyP; MnTE-2-PyP5+	Phase 2 Clinical	Duke University	Acne Vulgaris; Dermatitis, Atopic; Psoriasis; Rosacea	詳細
Tempol	MBM-02; OT-674; NSC-142784; MTS-02; MTS-10; MTS-01; APC-410; APC-400; REC-994; MBM-01; REC-0000994	Phase 2 Clinical	Mitos	Alopecia; Anus Neoplasms; Ataxia Telangiectasia; Cardiovascular Diseases; Coronavirus Disease 2019 (COVID-19); Drug-Related Side Effects and Adverse Reactions; Glioblastoma; Hemangioma, Cavernous, Central Nervous System; Mucositis; Ototoxicity; Prostatic Neoplasms	詳細
Superoxide dismutase analogue (LTT Bio-Pharma)	LT-1001; LT-0011; PC-SOD NE; PC-SOD; LT-1002	Phase 2 Clinical	LTT Bio-Pharma Co Ltd	Colitis, Ulcerative; Idiopathic Pulmonary Fibrosis; Myocardial Infarction; Peripheral Nervous System Diseases; Respiratory Distress Syndrome, Adult; Stroke	詳細
RAG-17	RAG-17; RD-12500	Phase 2 Clinical	Ractigen Therapeutics (Nantong) Co Ltd	Amyotrophic Lateral Sclerosis	詳細
ALN-SOD	ALN-SOD	Phase 2 Clinical	Alnylam Pharmaceuticals Inc	Amyotrophic Lateral Sclerosis	詳細
NI-005	AP-101 (AL-S Pharma); NI-005	Phase 2 Clinical	Al-S Pharma Ag	Amyotrophic Lateral Sclerosis	詳細
APB-102	APB-102; AMT-162	Phase 2 Clinical	University Of Massachusetts Medical School	Amyotrophic Lateral Sclerosis	詳細
NAS150	AEOL-10150; NAS150; NAS-150	Phase 1 Clinical	Aeolus Pharmaceuticals	Idiopathic Pulmonary Fibrosis; Lung Injury; Neoplasms; Supranuclear Palsy, Progressive	詳細
INS-1202	INS1202; INS-1202	Phase 1 Clinical	Insmed	Amyotrophic Lateral Sclerosis	詳細
[89Zr]Zr-DFO-AP-101		Phase 1 Clinical	Université De Sherbrooke	Amyotrophic Lateral Sclerosis; Tooth Diseases	詳細

市販薬剤に関する情報

英語名	研究コード	研究開発ステージ	会社	オリジナル製品名	最初に承認をした国	最初の適応症	最初に承認を受けた会社	承認された日付	適応症	臨床試験
Orgotein		Approved	Gt Biopharma Inc	Ontosein	Spain	Rheumatic Diseases; Cystitis; Radiation Injuries	null	1996-01-01	Cystitis; Radiation Injuries; Rheumatic Diseases	詳細
Cupric Sulfate/Manganese sulfate/Selenious acid/Zinc Sulfate		Approved	American Regent Inc	MULTRYS	United States	Dietary Supplement	American Regent Inc	2020-07-02	Dietary Supplement	詳細
Tofersen	99mTc-MAG3-BIIB067; ISIS-333611; BIIB-067; SODr/h333611; ISIS-SOD1Rx; IONIS SOD1Rx	Approved	Ionis Pharmaceuticals Inc, Ludwig Institute For Cancer Research	QALSODY, Qalsody, 凯盛迪	United States	Amyotrophic Lateral Sclerosis	Biogen Ma Inc, Biogen Inc	2023-04-25	Amyotrophic Lateral Sclerosis; Familial Amyotrophic Lateral Sclerosis	詳細