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Sortilin

Sortilin 詳細

英語名	Sortilin	市販薬剤の数	0
治験薬の数	3	ターゲットの別称	100 kDa NT receptor，NT3，Glycoprotein 95，LDLCQ6，NTR3，Gp95，Sortilin 1，Neurotensin receptor 3
研究＆開発段階	Phase 2 Clinical

英語名	Sortilin
ターゲットの別称	100 kDa NT receptor，NT3，Glycoprotein 95，LDLCQ6，NTR3，Gp95，Sortilin 1，Neurotensin receptor 3
市販薬剤の数	0
治験薬の数	3
研究＆開発段階	Phase 2 Clinical

Sortilin 製品リスト

属性
Protein (5)Cell (1)
製品ライブラリ
オンライン (6)
種
Human (3)Cynomolgus (1)Rat (1)Canine (1)
タグ
His Tag (4)His Tag & Avi Tag (1)- (1)
マーカー
Unconjugated (4)Biotin-labeled (1)- (1)

製品番号	種	発現システム	製品説明
CHEK-ATP155	Human	HEK293	HEK293/Human SORT1 Stable Cell Line
SON-H52H5	Human	HEK293	Human Sortilin / SORT1 Protein, His Tag, low endotoxin (MALS verified)
SON-H82E9	Human	HEK293	Biotinylated Human Sortilin / SORT1 Protein, His,Avitag™ (MALS & SPR verified)
SON-C52H3	Cynomolgus	HEK293	Cynomolgus Sortilin Protein, His Tag
SON-C52H4	Canine	HEK293	Canine Sortilin Protein, His Tag
SON-R52H3	Rat	HEK293	Rat Sortilin Protein, His Tag (MALS verified)

総数量6

Sortilinバックグランド

Sortilin is a multifunctional type-I transmembrane protein belonging to the Vps10p-domain receptor family (Vps10p-Domain Receptors, Vps10p-DRs). Sortilin plays a central role in cellular protein sorting, signal transduction, and metabolism. Its dysfunction is closely related to neurodegenerative diseases, metabolic syndrome, and cancer, and it is a potential therapeutic target for diseases.

Sortilin分子の別称

Sortilin,SORT1,100 kDa NT receptor,Glycoprotein 95,Gp95,Gp95LDLCQ6,Neurotensin receptor 3,NT3NTR3,Ntr3,sortilin 1,

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
VES-001	VES001; VES-001	Phase 2 Clinical	Vesper Bio APS	Dementia; Frontotemporal Dementia; Frontotemporal Lobar Degeneration	詳細
Latozinemab	AL-001; GSK-4527223	Phase 1 Clinical	Alector Inc, Glaxosmithkline Plc	Amyotrophic Lateral Sclerosis; Frontotemporal Dementia; Neurodegenerative Diseases	詳細
ARB-1-6	ARB-1-6; PQ-203	Phase 1 Clinical	ProteinQure Inc	Breast Neoplasms; Solid tumours; Triple Negative Breast Neoplasms	詳細