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TNFR2

TNFR2 詳細

英語名	Tumor necrosis factor receptor superfamily member 1B	市販薬剤の数	1
治験薬の数	8	ターゲットの別称	TNFR-II，TNFR80，TNF-RII，p80 TNF-alpha receptor，p75，Tumor necrosis factor receptor 2，Etanercept，TBP-2，Tumor necrosis factor receptor type II，TBPII，CD120b，TNF-R-II，CD120b Antigen，Tumor Necrosis Factor Beta Receptor，Soluble TNFR1B Variant 1，Tumor Necrosis Factor Binding Protein 2，TNFBR，TNF Receptor Superfamily Member 1B，TNFR2，P75 TNF Receptor，P75TNFR，TNFR1B，Tumor Necrosis Factor Receptor Superfamily， Member 1B，TNF-R75，TNF-R2
研究＆開発段階	Approved

英語名	Tumor necrosis factor receptor superfamily member 1B
ターゲットの別称	TNFR-II，TNFR80，TNF-RII，p80 TNF-alpha receptor，p75，Tumor necrosis factor receptor 2，Etanercept，TBP-2，Tumor necrosis factor receptor type II，TBPII，CD120b，TNF-R-II，CD120b Antigen，Tumor Necrosis Factor Beta Receptor，Soluble TNFR1B Variant 1，Tumor Necrosis Factor Binding Protein 2，TNFBR，TNF Receptor Superfamily Member 1B，TNFR2，P75 TNF Receptor，P75TNFR，TNFR1B，Tumor Necrosis Factor Receptor Superfamily， Member 1B，TNF-R75，TNF-R2
市販薬剤の数	1
治験薬の数	8
研究＆開発段階	Approved

TNFR2 製品リスト

属性
Protein (10)
製品ライブラリ
オンライン (10)
種
Human (4)Cynomolgus / Rhesus macaque (1)Mouse (3)Mouse & Human (1)Human & Mouse (1)
タグ
His Tag (5)His Tag & Avi Tag (2)Fc Tag (2)Fc Tag & Avi Tag (1)
マーカー
Unconjugated (7)Biotin-labeled (3)

製品番号	種	発現システム	製品説明
HOT TN2-H5227	Human	HEK293	Human TNFR2 / CD120b / TNFRSF1B Protein, His Tag, low endotoxin (MALS verified)
HOT TN2-H5253	Human	HEK293	Human TNFR2 / CD120b / TNFRSF1B Protein, Fc Tag (MALS verified)
HOT TN2-H82E3	Human	HEK293	Biotinylated Human TNFR2 / CD120b / TNFRSF1B Protein, His,Avitag™ (MALS verified)
HOT TN2-C52H7	Cynomolgus / Rhesus macaque	HEK293	Cynomolgus / Rhesus macaque TNFR2 / CD120b / TNFRSF1B Protein, His Tag
TN2-H82F3	Human	HEK293	Biotinylated Human TNFR2 / CD120b / TNFRSF1B Protein, Fc,Avitag™ (MALS verified)
TN2-M5254	Mouse	HEK293	Mouse TNFR2 / CD120b / TNFRSF1B Protein, Fc Tag (MALS verified)
TN2-M52H8	Mouse	HEK293	Mouse TNFR2 / CD120b / TNFRSF1B Protein, His Tag
TN2-M82E3	Mouse	HEK293	Biotinylated Mouse TNFR2 / CD120b / TNFRSF1B Protein, His,Avitag™ (MALS verified)
TN2-H52H3	Human & Mouse	HEK293	Human & Mouse TNFR2 / CD120b / TNFRSF1B Protein, His Tag, low endotoxin (MALS verified)
TN2-M52H3	Mouse & Human	HEK293	Mouse & Human TNFR2 / CD120b / TNFRSF1B Protein, His Tag, low endotoxin (MALS verified)

総数量10

TNFR2バックグランド

TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha. It has a much lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. TNFR2 mediates most of the metabolic effects of TNF-alpha.

TNFR2分子の別称

TNFRSF1B,CD120b,TBPII,TNF-R-II,TNF-R75,TNFBR,TNFR1B,TNFR2,TNFR80,p75,p75TNFR

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
LBL-019	LBL-019	Phase 2 Clinical	Nanjing Leadsbiolabs Co Ltd	Neoplasms	詳細
BI-1910	BI-1910	Phase 2 Clinical	Bioinvent International Ab	Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Solid tumours	詳細
BITR-2101	BITR-2101; BIR-2101; BITT2101; BITT-2101	Phase 1 Clinical	Boston Immune Technologies & Therapeutics	Infections; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Neoplasms	詳細
TRB-061	TRB-061	Phase 1 Clinical	Trex Bio Inc	Colitis; Dermatitis; Dermatitis, Atopic	詳細
NBL-020		Phase 1 Clinical	Shanghai Xinshi Biological Medicine Co Ltd	Neoplasms; Solid tumours	詳細
BC-011	BC-011	Phase 1 Clinical	Dragonboat Biopharmaceutical	Solid tumours	詳細
SIM1811-03	SIM1811-03; SIM0235; SIM-235	Phase 1 Clinical	Jiangsu Simcere Pharmaceutical Co Ltd	Lymphoma, T-Cell, Cutaneous; Neoplasms; Solid tumours	詳細
Emunkitug	HFB-2003; HFB-200301	Phase 1 Clinical	HiFiBiO Therapeutics	Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Germinoma; Melanoma; Mesothelioma; Neoplasm Metastasis; Neoplasms; Sarcoma; Skin Melanoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Testicular Neoplasms; Uterine Cervical Neoplasms	詳細

市販薬剤に関する情報

英語名	研究コード	研究開発ステージ	会社	オリジナル製品名	最初に承認をした国	最初の適応症	最初に承認を受けた会社	承認された日付	適応症	臨床試験
Recombinant human type II tumor necrosis factor receptor-antibody fusion protein(Hisun Biological)		Approved	Hisun Biopharmaceutical Co Ltd		Mainland China	Spondylitis, Ankylosing; Psoriasis; Arthritis, Rheumatoid	Hisun Biopharmaceutical Co Ltd	2015-04-09	Arthritis, Rheumatoid; Psoriasis; Spondylitis, Ankylosing	詳細