Immunohistochemistry (IHC) Antibody

Immunohistochemistry (IHC) is an antibody-based technique that utilizes the specific binding between antigens and antibodies. Through enzyme-labeled antibodies and chromogenic substrate reactions, it enables the localization, qualitative, and quantitative analysis of antigens within tissue cells. Due to its high specificity, sensitivity, and precise localization, IHC effectively integrates morphological and functional studies, making it widely applied across various fields of biological and medical research.

Due to its ability to visually and  qualitatively detect target proteins in tissue samples, IHC has become an essential validation method in the development of solid tumor-targeted therapies such as antibody-drug conjugates (ADCs) and TIL-based cell therapies. To better support drug development efforts, ACROBiosystems, through its ACRODiagnostic pathology platform, has conducted targeted IHC methodological validation for its antibody products, ensuring their specificity and suitability for IHC applications. Validation is performed using both healthy and tumor tissue samples to confirm accurate staining localization and applicability across representative cancer types. Furthermore, to meet diverse needs, our antibody development and pathology platforms offer customized IHC antibody development and screening services, allowing tailored solutions based on specific research requirements.