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Your Position: ホーム > Protein > S100A14 > S14-H5121

Human S100A14 Protein, His Tag

  • シノニム
    S100A14,S114,S100A15
  • ソース
    Human S100A14, His Tag (S14-H5121) is expressed from E. coli cells. It contains AA Met 1 - His 104 (Accession # Q9HCY8-1).
    Predicted N-terminus: Met 1
  • 分子特性
    Online(Met 1 - His 104) Q9HCY8-1

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 12.5 kDa. The protein migrates as 13 kDa under reducing (R) condition (SDS-PAGE).

  • エンドトキシン
    Less than 1.0 EU per μg by the LAL method.
  • 純度

    >95% as determined by SDS-PAGE.

  • 成分

    Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH8.0. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • 再構成

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 保存

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Human S100A14, His Tag (Cat. No. S14-H5121) SDS-PAGE gel

Human S100A14, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

  • バックグラウンド
    Protein S100-A14 (S100A14) is also known as S100 calcium-binding protein A14 (S114),which belongs to the S-100 family, containing one EF-hand domain.S100A14 is a homodimer can interact with AGER. S100A14 can modulate P53/TP53 protein levels, and play a role in the regulation of cell survival and apoptosis at different concentrations via receptor for advanced glycation end products (RAGE).S100A14 also plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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