Limited Edition Golden Llama is here! Check out how you can get one.
Limited Edition Golden Llama is here! Check out how you can get one.
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Offering SPR-BLI Services - Proteins provided for free!
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Here come GMP Grade Cytokines!Free Sample is available!
Here come GMP Grade Cytokines!Free Sample is available!
Project Name | Project Stage | Molecule Type | Host Species | Therapeutic Area | Indications |
DLL3 mAb - 01 | Lead | Solid Tumor | Small cell lung cancer |
Assay of human DLL3 protein on the μBeads surface by Flow cytometry. The human DLL3 protein conjugated on the μBeads (Cat. No. MBS-C018) surface were fluorescently stained using anti-human DLL3 antibody and PE anti-human IgG Fc Recombinant Antibody, and then analyzed by flow cytometry.
Expression analysis of human DLL3 on CHO/Human DLL3 Stable Cell Line by FACS.
Cell surface staining was performed on CHO/Human DLL3 Stable Cell Line or negative control cell using anti-human DLL3 antibody followed by staining with PE anti-human IgG Fc Antibody.
Bispecific T-cell Engager captured on Protein A Chip can bind Cynomolgus DLL3 (27-488), His Tag (Cat. No. DL3-C52H9) with an affinity constant of 1.02 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).
Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
---|---|---|---|---|---|---|---|---|---|---|
Tarlatamab | AMG-757 | Approved | Amgen Inc | Imdelltra | United States | Small Cell Lung Carcinoma | Amgen Inc | 2024-05-16 | Small Cell Lung Carcinoma; Neoplasms; Oligodendroglioma; Prostatic Neoplasms; Astrocytoma | Details |
Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
---|---|---|---|---|---|
MK-6070 | HPN-328; MK-6070 | Phase 2 Clinical | Harpoon Therapeutics | Small Cell Lung Carcinoma; Carcinoma, Neuroendocrine | Details |
Obrixtamig | BI-764532; OBT620 | Phase 2 Clinical | C.H. Boehringer Sohn Ag & Co. Kg | Small Cell Lung Carcinoma; Neoplasms; Neuroendocrine Tumors; Carcinoma, Neuroendocrine; Glioma | Details |
PT-217 | PT-217 | Phase 2 Clinical | Phanes Therapeutics Inc | Solid tumours; Small Cell Lung Carcinoma; Prostatic Neoplasms; Carcinoma, Neuroendocrine | Details |
ZG006 | ZG006; ZG-006 | Phase 2 Clinical | Gensun Biopharma Inc, Suzhou Zelgen Biopharmaceuticals Co Ltd | Solid tumours; Small Cell Lung Carcinoma; Neoplasms; Carcinoma, Neuroendocrine | Details |
89Zr-DFO-SC16.56 | 89Zr-DFO-SC16.56 | Phase 1 Clinical | Memorial Sloan Kettering Cancer Center | Small Cell Lung Carcinoma | Details |
IBI-3009 | IBI3009; IBI-3009 | Phase 1 Clinical | Innovent Biologics(Suzhou) Co Ltd | Solid tumours; Small Cell Lung Carcinoma; Carcinoma, Neuroendocrine | Details |
ALPS-12 | ALPS12; RG6524; RG-6524; ALPS 12 | Phase 1 Clinical | Chugai Pharmaceutical Co Ltd | Neoplasms; Small Cell Lung Carcinoma; Carcinoma, Neuroendocrine | Details |
BHP-01 | BHP-01; BHP01; α-PD-L1/4-1BB DLL3 CAR-T | Phase 1 Clinical | Chengdu Brilliant Pharmaceutical Co Ltd | Small Cell Lung Carcinoma | Details |
SHR-4849 | SHR-4849; SHR4849 | Phase 1 Clinical | Jiangsu Hengrui Pharmaceutical Group Co Ltd | Solid tumours | Details |
ZL-1310 | ZL-1310; ZL1310; YL212; YL-212 | Phase 1 Clinical | Zai Lab (Shanghai) Co Ltd, MediLink Therapeutics Co Ltd | Solid tumours; Small Cell Lung Carcinoma | Details |
FZ-AD005 | FZAD005; FZ-AD005 | Phase 1 Clinical | Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co Ltd | Solid tumours; Small Cell Lung Carcinoma; Carcinoma, Neuroendocrine | Details |
[89Zr]Zr-BI-764532 | Phase 1 Clinical | C.H. Boehringer Sohn Ag & Co. Kg, Boehringer Ingelheim Gmbh | Small Cell Lung Carcinoma; Carcinoma, Neuroendocrine | Details | |
ABD-147 | ABD-147; 225Ac-ABD147 | Phase 1 Clinical | Abdera Therapeutics Inc | Solid tumours; Small Cell Lung Carcinoma; Neuroendocrine Tumors | Details |
SNC115 | SNC115; SNC-115 | Phase 1 Clinical | Shanghai Simnova Biotechnology Co Ltd | Solid tumours; Small Cell Lung Carcinoma; Carcinoma, Neuroendocrine | Details |
OBT620 | OBT620 | Phase 1 Clinical | Boehringer Ingelheim Gmbh, Oxford Biotherapeutics Ltd | Small Cell Lung Carcinoma | Details |
DLL3-CAR-NK cells Therapy(Tianjin Medical University Cancer Institute and Hospital) | DLL3-CAR-NK cells | Phase 1 Clinical | Tianjin Medical University Cancer Institute And Hospital | Small Cell Lung Carcinoma | Details |
QLS-31904 | QLS31904; QLS-31904 | Phase 1 Clinical | Qilu Pharmaceutical Co Ltd | Solid tumours | Details |
LB-2102(Legend Biotechnology) | LB-2102 | Phase 1 Clinical | Nanjing Legend Biotechnology Co Ltd | Small Cell Lung Carcinoma; Neuroendocrine Tumors | Details |
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