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> MHCクラスI 複合体カスタムサービス
プロフェッショナルなMHC-ペプチド複合体の研究開発技術プラットフォーム
HEK293 発現系
さまざまなMHC I と抗原が利用可能
FITC/PE/APC/ビオチン標識を選択可能
成熟した生物活性検証プラットフォーム: SPR/ELISA/FACS など
| MHC Allele | |||||||
|---|---|---|---|---|---|---|---|
| Human classical MHC class I | Human classical MHC II | Mouse | Monkey | ||||
| Antigens |
|---|
2e5 of NY-ESO-1 TCR-HEK293 cells (pool) were stained with PE-Labeled Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) tetramer Protein（Fig B）and negative control protein respectively (Fig. A), and competitor-M represented competitor protein (Fig. C). PE signal was used to evaluate the binding activity
Anti-NY-ESO-1 antibody captured on CM5 chip via Anti-human IgG Fc antibodies surface can bind Biotinylated Human HLA-A0201 NY-ESO-1 (SLLMWITQC) Complex Protein (Cat. No. HL1-H82E6) with an affinity constant of 16.9 nM as determined in a SPR assay (Biacore 8K) (QC tested).
Anti-NY-ESO-1 antibody captured on CM5 chip via Anti-human IgG Fc antibodies surface can bind Human HLA-A0201 NY-ESO-1 (SLLMWITQC) Tetramer Protein (Cat. No. HL1-H52E8) with an affinity constant of 1.35 nM as determined in a SPR assay (Biacore 8K) (QC tested).
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