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Human CXCL3 Protein, Fc Tag (MALS verified)

  • Synonym
    CINC-2b, GRO3, GROg, MIP-2b, MIP2B, SCYB3
  • Source
    Human CXCL3 Protein, Fc Tag(CX3-H5263) is expressed from human 293 cells (HEK293). It contains AA Ala 35 - Asn 107 (Accession # P19876).
    Predicted N-terminus: Pro
  • Molecular Characterization
    CXCL3 Structure

    This protein carries a human IgG1 Fc tag at the N-terminus

    The protein has a calculated MW of 34 kDa. The protein migrates as 38-41 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
CXCL3 SDS-PAGE

Human CXCL3 Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

SEC-MALS
CXCL3 MALS images

The purity of Human CXCL3 Protein, Fc Tag (Cat. No. CX3-H5263) is more than 90% and the molecular weight of this protein is around 65-85 kDa verified by SEC-MALS.

  • Background
    This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils.
  • Clinical and Translational Updates

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