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Recombinant Monoclonal Anti-CD19 Antibody, Rabbit (4A6)

  • Background
    Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells (By similarity). Required for normal B cell differentiation and proliferation in response to antigen challenges. Required for normal levels of serum immunoglobulins, and for production of high-affinity antibodies in response to antigen challenge.
  • Host Species

    Rabbit

  • Clone

    4A6

  • Application

    IHC

  • Property
    1:1000
  • State
    Liquid
  • Positive Control
    Human Tonsil Tissues
  • Clonality
    Monoclonal
  • Synonym
    CD19
  • Research Field
    Cancer Drug Targets
  • Source
    Rabbit
  • Isotype
    IgG
  • Storage
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Typical Data
Control Sample
 CD19 CONTROL SAMPLE

Immunohistochemical analysis of paraffin embedded Human tonsil tissue labelled with HGS-S259 at 1/1000 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Cancer Sample
 CD19 CANCER SAMPLE CD19 CANCER SAMPLE

Immunohistochemical analysis of paraffin embedded human cancer tissue labelled with HGS-S259 at 1/1000 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

  • Clinical and Translational Updates

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ETA of in-stock products: 4 business days

価格(JPY) : 42,000

価格(JPY) : 168,000

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