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Your Position: ホーム > Protein > PTK7 > PT7-C52H3

Cynomolgus / Rhesus macaque PTK7 / CCK4 Protein, His Tag (MALS verified)

  • シノニム
    PTK7,CCK4,CCK-4,Tyrosine-protein kinase-like 7,Protein-tyrosine kinase 7,Protein-tyrosine kinase 7
  • ソース
    Cynomolgus / Rhesus macaque PTK7, His Tag (PT7-C52H3) is expressed from human 293 cells (HEK293). It contains AA Ala 39 - Thr 712 (Accession # A0A2K5VNI5-1). In the region Ala 39 - Thr 712, the AA sequence of Cynomolgus and Rhesus macaque PTK7 are homologus.
    Predicted N-terminus: Ala 39
  • 分子特性
    Online(Ala 39 - Thr 712) A0A2K5VNI5-1

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 76.5 kDa. The protein migrates as 100-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • エンドトキシン
    Less than 1.0 EU per μg by the LAL method.
  • 純度

    >95% as determined by SDS-PAGE.

  • 成分

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • 再構成

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 保存

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Cynomolgus / Rhesus macaque PTK7, His Tag (Cat. No. PT7-C52H3) SDS-PAGE gel

Cynomolgus / Rhesus macaque PTK7, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

SEC-MALS
Cynomolgus / Rhesus macaque PTK7, His Tag (Cat. No. ) MALS images

The purity of Cynomolgus / Rhesus macaque PTK7, His Tag (Cat. No. PT7-C52H3) is more than 85% and the molecular weight of this protein is around 80-116 kDa verified by SEC-MALS.

  • バックグラウンド
    PTK7, highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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