PE-Labeled Monoclonal Anti-Human CD11b Antibody, Mouse IgG1 (AS673) (0.03% Proclin)

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製品番号/仕様
価格
数量
FABm066-01-200tests (50tests X 4)
$240.00
ETA of in-stock products:2 business days
総アイテム数 製品金額$ 0

製品詳細

  • Source

    Monoclonal Anti-Human CD11b Antibody, Mouse IgG1 (AS673) is a mouse monoclonal antibody, which provides higher batch consistency and long term security of supply.

  • Clone

    AS673

  • Isotype

    Mouse IgG1, Kappa

  • Host Species

    Mouse

  • Reactivity

    Human

  • Immunogen

    Purified Human CD11b Protein

  • Conjugate

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • Specificity

    This product is a specific antibody specifically reacts with CD11b protein.

  • Application

    Flow Cytometry (Evaluation of the expression of CD11b on Human cells).

  • Recommended Dilution

    1:20

  • Isotype Control

    The isotype control is sold separately; please refer to Cat. No. DNP-PM1 for product information.

  • Form

    Liquid

  • Formulation

    Supplied as 0.2 μm-filtered solution in PBS (pH 7.4) containing 0.03% ProClin 300 and 0.2% BSA, with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Shipping

    Liquid product is shipped at blue ice.

  • Storage

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. Store at 2-8 °C for 12 months.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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データ表示

  • Bioactivity-FACS

     CD11b FACS

    Flow cytometric analysis of Human PBMC cell staining with PE-Labeled Monoclonal Anti-Human CD11b Antibody, Mouse IgG1 (AS673) (Cat. No. FABm066-01) at 1:20 dilution (5 μL of the antibody stock solution corresponds to labeling of 1e6 cells in a final volume of 100 µL), compared with isotype control antibody. PE signal was used to evaluate the binding activity (QC tested).

    Protocol

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バックグランド

CD11b, a 170 kDa glycoprotein also named αM integrin, Mac-1 α subunit, Mol, CR3 and Ly-40, is an integrin family member. It is primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells and subsets of T/B cells, and non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 mediates cell-cell interactions by binding ligands including ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b and fibrinogen. As a specific marker of the 165 kDa α subunit of CD11b/CD18 heterodimer, CD11b serves as a key target for flow cytometry analysis of immune cell functions.

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