Recombinant Monoclonal Anti-CD19 Antibody, Rabbit (4A6)

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Cat. No. / Size
Price
Qty
HGS-S259-20ul
$125.00
HGS-S259-100ul
$360.00
ETA of in-stock products:2 business days

Product Details

  • Background

    Recombinant Monoclonal Anti-CD19 Antibody, Rabbit (4A6) is a CD19 primary antibody for IHC application. Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells (By similarity). Required for normal B cell differentiation and proliferation in response to antigen challenges. Required for normal levels of serum immunoglobulins, and for production of high-affinity antibodies in response to antigen challenge.

  • Product Specifications

    Host Species
    Rabbit
    Isotype
    Rabbit IgG, Rabbit Kappa
    Clone
    4A6
    Application
    IHC-P
    Dilution Ratio
    1: 500 - 1: 2000
    Form
    Liquid
    Clonality
    Monoclonal
    Reactivity
    Human
    Synonyms
    Leu-12
    Concentration
    0.9~1.1 mg/ml
    Specificity
    React with CD19 protein on the membrane of target cell/tissue
    Purification Tech
    Protein A
    Preservation
    PBS, BSA, Glycerol
  • Experiment Protocol

    LEICA Experiment Protocol

  • Storage

    Shipped at 4°C, Blue Ice. Store at +4°C for short term (1-2 weeks). Store at -20°C for long term.
    Avoid freeze / thaw cycle. Upon delivery aliquot. The shelf life is 30 days from the date of opening.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • Sample Staining Data

     CD19 SAMPLE STAINING DATA
  •  CD19 SAMPLE STAINING DATA

    Immunohistochemical analysis of paraffin embedded human cancer tissue labelled with HGS-S259 at 1/1000 dilution.
    Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

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Drug Development Progress
  • English Name:

    B-lymphocyte antigen CD19

  • Category:

  • Approved Drugs:

    14 Details

  • Drugs in Clinical Trials:

    435 Details

  • Highest Development Stage:

    Approved

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