言語を選択
新規登録
お気に入りに追加

PE-Labeled Monoclonal Anti-Human CD43 Antibody, Mouse IgG1 (AS672) (0.03% Proclin)

COADS MS
DS

ユーザーレビュー
製品番号/仕様
価格
数量
FABm065-01-200tests (50tests X 4)
$200.00
ETA of in-stock products:2 business days
総アイテム数 製品金額$ 0
推奨新製品
関連アイテム

製品詳細

  • Source

    Monoclonal Anti-Human CD43 Antibody, Mouse IgG1 (AS672) is a mouse monoclonal antibody, which provides higher batch consistency and long term security of supply.

  • Clone

    AS672

  • Isotype

    Mouse IgG1, Kappa

  • Host Species

    Mouse

  • Reactivity

    Human

  • Immunogen

    Purified Human CD43 Protein

  • Conjugate

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • Specificity

    This product is a specific antibody specifically reacts with CD43 protein.

  • Application

    Flow Cytometry (Evaluation of the expression of CD43 on Human cells).

  • Recommended Dilution

    1:20

  • Isotype Control

    The isotype control is sold separately; please refer to Cat. No. DNP-PM1 for product information.

  • Form

    Liquid

  • Formulation

    Supplied as 0.2 μm-filtered solution in PBS (pH 7.4) containing 0.03% ProClin 300 and 0.2% BSA, with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Shipping

    Liquid product is shipped at blue ice.

  • Storage

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. Store at 2-8 °C for 12 months.

  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

お客様はこちらも閲覧

データ表示

  • Bioactivity-FACS

    CD43 FACS

    Flow cytometric analysis of Human Jurkat cells staining with PE-Labeled Monoclonal Anti-Human CD43 Antibody, Mouse IgG1 (AS672) (Cat. No. FABm065-01) at 1:20 dilution (5 μL of the antibody stock solution corresponds to labeling of 1e6 cells in a final volume of 100 µL), compared with isotype control antibody. PE signal was used to evaluate the binding activity (QC tested).

    Protocol

ユーザーレビュー
コメントを投稿

バックグランド

CD43, also designated Ly-48, leukosialin, sialophorin, leukocyte sialoglycoprotein and W3/13, is a large type I transmembrane glycoprotein enriched with O-glycosylation and sialylation sites. It binds to CD54 (ICAM-1), CD62E, CD169 (Siglec-1), CD328 (Siglec-7) and MHC Class I molecules. Widely expressed on T lymphocytes, thymocytes, monocytes, granulocytes, bone marrow stem cells, pre-B cells, activated B cells and plasma cells—but absent on resting peripheral blood B cells, red blood cells and nonhematopoietic cells—CD43 modulates leukocyte functions (bidirectional adhesion, T cell costimulation, apoptosis induction) via intercellular interactions. Enzymatic shedding of activated leukocyte surface CD43 may exert negative regulation on adaptive immune responses, making it a valuable target for flow cytometry analysis.

最新の進展

 
医薬品開発の進捗
  • 英語名：

    Leukosialin

  • カテゴリ：

  • 市販の医薬品数：

    0 詳細

  • 治験医薬品数：

    0 詳細

  • 最新の開発ステージ：

    Preclinical

お問い合わせ
医薬品候補ライセンス
他の関連情報
  • 製品情報
  • 製品詳細
  • お客様はこちらも閲覧
  • データ表示
  • ユーザーレビュー
  • 背景
共有：

採用情報法的規制サイトマッププライバシーポリシー利用規約
ウェブサイトに関するフィードバック
お問い合わせ

お問い合わせ
グローバル：+1 800-810-0816(Toll Free)

メールアドレス
order.jp@acrobiosystems.com

アクロバイオシステムズ株式会社
〒101-0051
東京都千代田区神田神保町1-32-8