Monoclonal Anti-HRSV F Antibody, Human IgG1 (Palivizumab)

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Cat. No. / Size
Price
Qty
HRF-M789-100ug
$415.00
HRF-M789-1mg
$2735.00
ETA of in-stock products:2 business days

Product Details

  • Source

    Monoclonal Anti-HRSV F Antibody, Human IgG1 (Palivizumab) is a chimeric monoclonal antibody recombinantly expressed in HEK293, which combines the variable region of a mouse monoclonal antibody with human constant domain.

  • Antibody Type

    Recombinant Monoclonal

  • Isotype

    Human IgG1, Kappa

  • Specificity

    This product is a specific antibody specifically reacts with HRSV F-Palivizumab.

  • Purification

    Protein A purified / Protein G purified.

  • Concentration

    Please refer to the Certificate of Analysis (CoA).

  • Form

    Lyophilized

  • Formulation

    Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Reconstitution

    Please refer to the Certificate of Analysis (CoA) for specific instructions.

  • Shipping

    Lyophilized product is shipped at ambient temperature.

  • Storage

    For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • Bioactivity-ELISA

     HRSV F ELISA

    Immobilized HRSV (A) Post-fusion glycoprotein F0, His Tag (Cat. No. RSF-V52H6) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-HRSV F Antibody, Human IgG1 (Palivizumab) (Cat. No. HRF-M789) with a linear range of 0.3-5 ng/mL (QC tested).

    Protocol
  •  HRSV F ELISA

    Immobilized HRSV (B) Post-fusion glycoprotein F0, His Tag (Cat. No. RSF-V52H9) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-HRSV F Antibody, Human IgG1 (Palivizumab) (Cat. No. HRF-M789) with a linear range of 0.3-5 ng/mL (QC tested).

    Protocol
  •  HRSV F ELISA

    Immobilized HRSV (A) Pre-fusion glycoprotein F0, His Tag (Cat. No. RSF-V52H7) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-HRSV F Antibody, Human IgG1 (Palivizumab) (Cat. No. HRF-M789) with a linear range of 0.3-5 ng/mL (Routinely tested).

    Protocol
  •  HRSV F ELISA

    Immobilized HRSV (B) Pre-fusion glycoprotein F0, His Tag (Cat. No. RSF-V52H8) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-HRSV F Antibody, Human IgG1 (Palivizumab) (Cat. No. HRF-M789) with a linear range of 0.3-5 ng/mL (Routinely tested).

    Protocol

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Background

Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life. The RSV fusion glycoprotein (RSV F) is the principal target of RSV neutralizing antibodies in human sera. The RSV F is a type I viral fusion protein synthesized as inactive, single-chain polypeptides that assemble into trimers. RSV F fuses the viral and host cell membranes by irreversible protein refolding from the labile prefusion conformation to the stable post-fusion conformation.
Antibody Palivizumab, a humanized monoclonal antibody targeting the antigenic site II region of the RSV F protein.

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