Human IgG1 (L234A, L235A) Kappa Isotype Control (mAb, carrier free, MALS verified)

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Cat. No. / Size
Price
Qty
DNP-C18P1-100ug
$165.00
DNP-C18P1-1mg (250ug X 4)
$720.00
DNP-C18P1-25mg
$1545.00
DNP-C18P1-100mg
$5150.00
ETA of in-stock products:2 business days

Product Details

  • Source

    Human IgG1 (L234A, L235A) Kappa Isotype Control (mAb) is a recombinant chimeric monoclonal antibody expressed in HEK293, which combines the variable region of a mouse monoclonal antibody with human constant domain.

  • Antibody Type

    Recombinant Monoclonal

  • Isotype

    Human IgG1 (L234A, L235A), Kappa

  • Host Species

    Human

  • Specificity

    This product is a specific antibody specifically reacts with DNP.

  • Application

    Application
    Recommended Usage
    ELISA
    1:2000-1:20000
  • Purification

    Protein A purified / Protein G purified.

  • Aggregation

    Less than 5%, as determined by SEC-MALS.

  • Concentration

    Please refer to the Certificate of Analysis (CoA).

  • Form

    Lyophilized

  • Formulation

    Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

    Please contact us for customized product forms or formulations.

    25 mg or larger size will be supplied as liquid and shipped by dry ice. Please inquire the dry ice shipping cost.

  • Reconstitution

    Please refer to the Certificate of Analysis (CoA) for specific instructions.

  • Shipping

    Lyophilized product is shipped at ambient temperature.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • Bioactivity-ELISA

     IgG control ELISA

    Immobilized DNP-Albumin Conjugate, Bovine at 10 μg/mL (100 μL/well) can bind Human IgG1 (L234A, L235A) Kappa Isotype Control (mAb) (Cat. No. DNP-C18P1) with a linear range of 0.1-4 ng/mL (QC tested).

    Protocol

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Background

Fc engineered isotype controls are designed to evaluate effector functions such as FcγR binding, FcRn interaction, ADCC, and CDC. Each variant is functionally validated, providing a reliable negative control framework for antibody mechanism studies and therapeutic development.

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