PCSK9 [Biotinylated] : LDL R Inhibitor Screening ELISA Assay Pair

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製品番号/仕様
価格
数量
EP-103-96tests
$715.00
ETA of in-stock products:2 business days
総アイテム数 製品金額$ 0

製品詳細

  • Materials Provided

    ID
    Components
    Size
    A006-214
    Human LDL R
    35 μg
    A007-214
    Biotinylated Human PCSK9
    10 μg
    A003-214
    Streptavidin-HRP
    10 μg
    PC9-NA003
    Anti-PCSK9 Neutralizing Antibody
    40 μg

  • Product Overview

    PCSK9 [Biotinylated] : LDL R Inhibitor Screening ELISA Assay Pair is based on a competition-ELISA method, is used to screening for inhibitors of human PCSK9 binding to human LDL R. The kit is designed to provide a reliable solution for the screening of antibodies and small molecule inhibitors in the early stages, as well as QC release, to help researchers quickly screen and validate drugs, effectively improving research and development efficiency. It can also be used as a universal detection tool to identify the ability of human PCSK9 to bind to human LDL R.

  • Reconstitution

    See Certificate of Analysis for details of reconstitution instruction and specific concentration.

  • Storage

    1. Unopened kit should be stored at -25~-15℃ upon receiving.

    2. Find the expiration date on the outside packaging and do not use reagents past their expiration date.

    3. The opened kit should be stored per components table. The shelf life is 30 days from the date of opening.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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  • Typical Data 

    Please refer to DS document for the assay protocol.

     PCSK9 TYPICAL DATA

    INHIBITION OF PCSK9 [BIOTINYLATED]: LDL R BINDING BY ANTI-PCSK9 NEUTRALIZING ANTIBODY
    Serial dilutions of anti-PCSK9 neutralizing antibody (Catalog # PC9-NA003) (1:2 serial dilutions, from 20 μg/mL to 0.04 μg/mL or 133.33 nM to 0.26 nM) were added into Biotinylated PCSK9: LDL R binding reactions. Background was subtracted from data points prior to log transformation and curve fitting (QC tested).

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最新の進展

 
医薬品開発の進捗
  • 英語名:

    Proprotein convertase subtilisin kexin type 9

  • カテゴリ:

  • 市販の医薬品数:

    8 詳細

  • 治験医薬品数:

    35 詳細

  • 最新の開発ステージ:

    Approved

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