Human CCL5/RANTES Protein, Tag Free

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製品番号/仕様
価格
数量
CC5-H5113-20ug
$185.00
CC5-H5113-50ug
$370.00
CC5-H5113-1mg (200ug X 5)
$3400.00
ETA of in-stock products:2 business days
総アイテム数 製品金額$ 0

製品詳細

  • Synonyms

    EoCP, Eosinophil chemotactic cytokine, SIS-delta, Small-inducible cytokine A5, T cell-specific protein P228, TCP228, D17S136E, SCYA5, CCL5, C-C motif chemokine 5 T-cell-specific protein RANTES

  • Source

    Human CCL5/RANTES Protein, Tag Free (CC5-H5113) is expressed from E. coli cells. It contains AA Ser 24 - Ser 91 (Accession # P13501-1).

    Predicted N-terminus: Ser 24

    Request for sequence
  • Molecular Characterization

    CCL5 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries no "tag".

    The protein has a calculated MW of 7.9 kDa. The protein migrates as 8-9 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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データ表示

  • SDS-PAGE

    CCL5 SDS-PAGE

    Human CCL5/RANTES Protein, Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • Bioactivity-ELISA

     CCL5 ELISA

    Immobilized Human CCL5/RANTES Protein, Tag Free (Cat. No. CC5-H5113) at 5 μg/mL (100 μL/well) can bind Human CCR2 Full Length Protein, Flag,His Tag (Cat. No. CC2-H52D4) with a linear range of 0.005-0.313 μg/mL (QC tested).

    Protocol
  •  CCL5 ELISA

    Immobilized Human CCL5/RANTES Protein, Tag Free (Cat. No. CC5-H5113) at 5 μg/mL (100 μL/well) can bind Human CCR5, Flag,His Tag (Cat. No. CC5-H52D1) with a linear range of 0.005-0.313 μg/mL (Routinely tested).

    Protocol

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バックグランド

C-C chemokine ligand 5 (CCL5), also known as RANTES, is a target gene of NF-kappaB, and is expressed by T lymphocytes, macrophages, platelets, synovial fibroblasts, tubular epithelium, and certain types of tumour cells. CCL5 plays a role in recruiting a variety of leukocytes into inflammatory sites including T cells, macrophages, eosinophils, and basophils. CCL5 activity is mediated through its binding to CCR1, CCR3, and mainly CCR5.

最新の進展

 
医薬品開発の進捗
  • 英語名:

    C-C motif chemokine 5

  • カテゴリ:

  • 市販の医薬品数:

    0 詳細

  • 治験医薬品数:

    2 詳細

  • 最新の開発ステージ:

    Phase 2 Clinical

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