Human CD9 Full Length Protein (VLP)

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製品番号/仕様
価格
数量
CD9-H52P3-20ug
$620.00
CD9-H52P3-100ug
$1235.00
CD9-H52P3-500ug (250ug X 2)
$4305.00
ETA of in-stock products:2 business days
総アイテム数 製品金額$ 0

製品詳細

  • Application

    1. Immunization
    2. Cell based assay (FACS or functional assay)
    3. Screening (ELISA)
  • Synonyms

    CD9, MIC3, TSPAN29, GIG2, MRP1, BTCC1, DRAP27, 5H9

  • Source

    Human CD9 Full Length Protein (VLP) (CD9-H52P3) is expressed from human 293 cells (HEK293). It contains AA Pro 2 - Val 228 (Accession # P21926).

    Predicted N-terminus: Met

  • Molecular Characterization

    *The isotype control of empty/mock VLP (Cat. No. VLP-N5213) is sold separately and not included in protein, you can follow the link for product information.

    1. Structure

      Virus-like particles (VLPs) are protein particles that mimic the shape of viruses but lack a viral genome, and incorporating transmembrane proteins on the external surface.

    2. Synthesis Process

      Envelope virus-like particles (eVLPs) are produced by co-expressing target membrane proteins with viral structural proteins in mammalian cells, enabling native embedding of membrane proteins into the lipid bilayer during VLP budding. This approach preserves authentic conformation, post-translational modifications, and orientation, while creating a completely detergent-free environment with repetitive multivalent display and strong immunogenicity making them ideal for immunization, binding assays in antibody discovery and screening (ELISA), and cell-based assays such as FACS, etc.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >95% as determined by SEC-HPLC.

  • Formulation

    The VLPs are highly immunogenic, so the immunization strategy should be optimized (antigen dose, regimen and adjuvant).

    Supplied as 0.2 μm filtered solution in PBS, Arginine, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 12 months under sterile conditions.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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データ表示

  • SEC-HPLC

    CD9 SEC-HPLC

    The purity of Human CD9 Full Length Protein (VLP) (Cat. No. CD9-H52P3) was greater than 95% as determined by SEC-HPLC.

  • Bioactivity-ELISA

     CD9 ELISA

    Immobilized Human CD9 Full Length Protein (VLP) (Cat. No. CD9-H52P3) at 5 μg/mL (100 μL/well) can bind Anti-CD9 Antibody, Human IgG1 with a linear range of 0.002-0.156 μg/mL (QC tested).

    Protocol
  • Identity-DLS

     CD9 DLS

    The mean peak Radius of VLP is 65-85 nm with more than 95% intensity as determined by dynamic light scattering (DLS).

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バックグランド

A tetraspanin broadly expressed on immune cells, platelets, and exosomes. It regulates cell fusion, sperm-egg fusion, and tumor cell motility. CD9 is a canonical exosome marker. In oncology, CD9 can function as either a metastasis suppressor or promoter depending on the cellular context and integrin associations.

最新の進展

 
医薬品開発の進捗
  • 英語名:

    CD9 antigen

  • カテゴリ:

  • 市販の医薬品数:

    0 詳細

  • 治験医薬品数:

    1 詳細

  • 最新の開発ステージ:

    Phase 1 Clinical

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