製品詳細
Synonyms
CTLA4, CD152
Source
Cynomolgus / Rhesus macaque CTLA-4, His Tag (CT4-C5227) is expressed from human 293 cells (HEK293). It contains AA Ala 37 - Ser 160 (Accession # G7PL88-1). In the region Ala 37 - Ser 160, the amino acid sequences of Cynomolgus and Rhesus macaque CTLA-4 are identical.
Predicted N-terminus: Ala 37
Request for sequenceMolecular Characterization

Other Tags and Version Biotin & Other Labeled Version
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 14.1 kDa. The protein migrates as 19-24 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
The protein is designed as a dimer.
Endotoxin
Less than 0.1 EU per μg by the LAL method / rFC method.
Purity
>90% as determined by SDS-PAGE.
>95% as determined by SEC-MALS.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Shipping and Storage
This product is shipped at ambient temperature.
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System
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データ表示
SDS-PAGE

Cynomolgus / Rhesus macaque CTLA-4, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.
SEC-MALS

The purity of Cynomolgus / Rhesus macaque CTLA-4, His Tag (Cat. No. CT4-C5227) is more than 95% and the molecular weight of this protein is around 22-32 kDa verified by SEC-MALS.
Report
Bioactivity-ELISA

Immobilized Cynomolgus / Rhesus macaque B7-1, Fc Tag (Cat. No. CD0-C5252) at 2 μg/mL (100 μL/well) can bind Cynomolgus / Rhesus macaque CTLA-4, His Tag (Cat. No. CT4-C5227) with a linear range of 0.06-0.5 ng/mL (QC tested).
Protocol
Immobilized Cynomolgus / Rhesus macaque B7-2, Fc Tag (Cat. No. CD6-C5254) at 2 μg/mL (100 μL/well) can bind Cynomolgus / Rhesus macaque CTLA-4, His Tag (Cat. No. CT4-C5227) with a linear range of 4-31 ng/mL (Routinely tested).
Protocol
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最新の進展
- 英語名:
Cytotoxic T-Lymphocyte-Associated Antigen 4
- カテゴリ:
- 市販の医薬品数:
5 詳細
- 治験医薬品数:
65 詳細
- 最新の開発ステージ:
Approved
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