Human CXCL2 Protein, His Tag

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製品番号/仕様
価格
数量
CX2-H52H3-100ug
$360.00
CX2-H52H3-1mg (500ug X 2)
$2380.00
ETA of in-stock products:2 business days
総アイテム数 製品金額$ 0

製品詳細

  • Synonyms

    C-X-C motif chemokine 2, Growth-regulated protein beta, Gro-beta, Macrophage inflammatory protein 2-alpha, MIP2-alpha, GRO2, GROB, MIP2A, SCYB2

  • Source

    Human CXCL2 Protein, His Tag (CX2-H52H3) is expressed from human 293 cells (HEK293). It contains AA Ala 35 - Asn 107 (Accession # P19875-1).

    Predicted N-terminus: Gly

    Request for sequence
  • Molecular Characterization

    CXCL2 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 9.9 kDa. The protein migrates as 11-12 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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データ表示

  • SDS-PAGE

    CXCL2 SDS-PAGE

    Human CXCL2 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • Bioactivity-ELISA

     CXCL2 ELISA

    Immobilized Human CXCL2 Protein, His Tag (Cat. No. CX2-H52H3) at 5 μg/mL (100 μL/well) can bind Human CXCR2 Protein, Flag,His Tag (Cat. No. CX2-H55D3) with a linear range of 2-39 ng/mL (QC tested).

    Protocol

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バックグランド

Chemokine (C-X-C motif) ligand 2 (CXCL2) is a small cytokine belonging to the CXC chemokine family. It is also known as macrophage inflammatory protein 2-alpha (MIP2‑alpha), growth-regulated protein beta (GRO‑β), and GRO oncogene‑2 (GRO‑2). CXCL2 is 90% identical in amino acid sequence to a related chemokine, CXCL1. This chemokine is secreted by monocytes and macrophages and is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells. CXCL2 mobilizes cells via interaction with a cell surface chemokine receptor called CXCR2. Like related chemokines, CXCL2 is also a powerful neutrophil chemoattractant and is involved in many immune processes, including wound healing, cancer metastasis, and angiogenesis.

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