Influenza A Virus (A/Texas/37/2024) HA (H5N1) Protein, His Tag (MALS verified)

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製品番号/仕様
価格
数量
H51-V52H3-100ug
$350.00
H51-V52H3-1mg
$2680.00
ETA of in-stock products:2 business days
総アイテム数 製品金額$ 0

製品詳細

  • Synonyms

    Hemagglutinin/HA (Influenza Virus)

  • Source

    Influenza A Virus (A/Texas/37/2024) HA (H5N1) Protein, His Tag (H51-V52H3) is expressed from human 293 cells (HEK293). It contains AA Asp 17 - Ile 531 (Accession # EPI3171488 (341 KRRKR 345-TETR), GISAID).

    Predicted N-terminus: Asp 17

    Request for sequence

  • Molecular Characterization

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 63.7 kDa. The protein migrates as 90 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

    The protein is designed as a trimer.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 0.1 M Sodium citrate, pH5.5 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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データ表示

  • SDS-PAGE

    Hemagglutinin/HA (Influenza Virus) SDS-PAGE

    Influenza A Virus (A/Texas/37/2024) HA (H5N1) Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    Hemagglutinin/HA (Influenza Virus) SEC-MALS

    The purity of Influenza A Virus (A/Texas/37/2024) HA (H5N1) Protein, His Tag (Cat. No. H51-V52H3) is more than 90% and the molecular weight of this protein is around 215-255 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     Hemagglutinin/HA (Influenza Virus) ELISA

    Immobilized Influenza A Virus (A/Texas/37/2024) HA (H5N1) Protein, His Tag (Cat. No. H51-V52H3) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Influenza A (A/Hong Kong/483/1997) HA (H5N1) Antibody, Human IgG1 (1A4) (Cat. No. HA1-MY2026) with a linear range of 0.06-4 ng/mL (QC tested).

    Protocol

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Influenza, commonly known as 'the flu', is an infectious disease of birds and mammals caused by RNA viruses of the family Orthomyxoviridae, the influenza viruses. The virus is divided into three main types (Influenzavirus A, Influenzavirus B, and Influenzavirus C), which are distinguished by differences in two major internal proteins (hemagglutinin (HA) and neuraminidase (NA), which are the most important targets for the immune system. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle which makes it a great target for vaccine studies.

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