PE-Labeled Human HLA-A*02:01&B2M&EBV EBNA3C (LLDFVRFMGV) Tetramer Protein

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Cat. No. / Size
Price
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HLC-HP2H3-25ug
$410.00
HLC-HP2H3-200ug (100ug X 2)
$2350.00
ETA of in-stock products:2 business days

Product Details

  • Synonyms

    HLA-A*0201 & B2M & EBV EBNA3C (LLDFVRFMGV)

  • Source

    PE-Labeled Human HLA-A*02:01&B2M&EBV EBNA3C (LLDFVRFMGV) Tetramer Protein (HLC-HP2H3) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & LLDFVRFMGV peptide (Accession # AAA59606.1 (HLA-A*02:01) & P61769-1 (B2M) & LLDFVRFMGV).

    Predicted N-terminus: Gly 25 & Leu

    Request for sequence
  • Molecular Characterization

    PE-Labeled Human HLA-A*02:01&B2M&EBV EBNA3C (LLDFVRFMGV) Tetramer Protein is assembled by biotinylated monomer (HLC-H82E8) and PE-labeled streptavidin.

    Biotinylated Human HLA-A*02:01&B2M&EBV EBNA3C (LLDFVRFMGV) Complex Protein is produced by co-expression of HLA and B2M loaded with EBV EBNA3C peptide. Biotinylated Human HLA-A*02:01&B2M&EBV EBNA3C (LLDFVRFMGV) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).

  • Conjugate

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, 1% BSA, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Background

The peptide LLDFVRFMGV, derived from the Epstein-Barr virus nuclear antigen EBNA3C, is presented by the HLA-A*02:01/β2m complex. This peptide-MHC complex serves as a major target for cytotoxic T lymphocytes (CTLs) in the immune control of EBV infection. Its robust immunogenicity makes it a key antigen of interest for studying EBV-specific T-cell responses and for developing immunotherapies against EBV-associated diseases.

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