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製品詳細
Synonyms
IL-11, Interleukin-11, AGIF, Oprelvekin, IL11
Source
Human IL-11, Fc Tag (IL1-H5269) is expressed from human 293 cells (HEK293). It contains AA Pro 22 - Leu 199 (Accession # P20809-1).
Predicted N-terminus: Pro
Request for sequenceMolecular Characterization
Other Tags and Version Biotin & Other Labeled Version
This protein carries a human IgG1 Fc tag at the N-terminus.
The protein has a calculated MW of 45.6 kDa. The protein migrates as 47-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
Less than 0.01 EU per μg by the LAL method / rFC method.
Purity
>95% as determined by SDS-PAGE.
>95% as determined by SEC-MALS.
Formulation
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System
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データ表示
SDS-PAGE
Human IL-11, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
SEC-MALS
The purity of Human IL-11, Fc Tag (Cat. No. IL1-H5269) is more than 95% and the molecular weight of this protein is around 80-105 kDa verified by SEC-MALS.
Report
Bioactivity-ELISA
Immobilized Human IL-11 R alpha, His Tag (Cat. No. ILR-H52H5) at 5 μg/mL (100 μL/well) can bind Human IL-11, Fc Tag (Cat. No. IL1-H5269) with a linear range of 0.2-10 ng/mL (QC tested).
Protocol
Immobilized Human IL-11, Fc Tag (Cat. No. IL1-H5269) at 5 μg/mL (100 μL/well) can bind Human IL-11 R alpha, His Tag (Cat. No. ILR-H52H5) with a linear range of 0.008-0.5 μg/mL (Routinely tested).
Protocol
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最新の進展
医薬品開発の進捗- 英語名：
Interleukin-11
- カテゴリ：
- 市販の医薬品数：
1 詳細
- 治験医薬品数：
4 詳細
- 最新の開発ステージ：
Approved
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