Human IL-18 R beta / IL-1 R7 Protein, His Tag, low endotoxin

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Cat. No. / Size
Price
Qty
ILB-H52H8-100ug
$225.00
ILB-H52H8-1mg (500ug X 2)
$1560.00
ETA of in-stock products:2 business days

Product Details

  • Synonyms

    IL-18 R beta, IL-1 R7, CD218b, CDw218b, IL-1 R7, IL-18 R beta, IL-18 receptor accessory protein, IL-18 receptor beta, IL18R beta, IL-18RAcP

  • Source

    Human IL-18 R beta, His Tag (ILB-H52H8) is expressed from human 293 cells (HEK293). It contains AA Phe 20 - Arg 356 (Accession # O95256-1).

    Predicted N-terminus: Phe 20

    Request for sequence
  • Molecular Characterization

    IL-18 R beta Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 40.3 kDa. The protein migrates as 55-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 0.01 EU per μg by the LAL method / rFC method.

  • Purity

    >95% as determined by SDS-PAGE.

    >95% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • SDS-PAGE

    IL-18 R beta SDS-PAGE

    Human IL-18 R beta, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

  • SEC-MALS

    IL-18 R beta SEC-MALS

    The purity of Human IL-18 R beta, His Tag (Cat. No. ILB-H52H8) is more than 95% and the molecular weight of this protein is around 40-60 kDa verified by SEC-MALS.

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Background

IL-18 R beta (IL-1R7), also known as IL18RAP (Interleukin 18 Receptor Accessory Protein), is a member of the IL-1 family. Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation.

Recent Advances

 
Drug Development Progress
  • English Name:

    Interleukin-18 receptor accessory protein

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