Product Details
Synonyms
IL-2 R beta & IL-2 R gamma, IL-2RB & IL-2RG
Source
Cynomolgus IL-2 R beta&IL-2 R gamma Heterodimer Protein, His Tag&Twin-Strep Tag (ILG-C5284) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Thr 240 & Leu 23 - Pro 255 (Accession # Q38J85-1 & A0A2K5VGJ6).
Predicted N-terminus: Ala 27 & Leu 23
Request for sequenceMolecular Characterization

Other Tags and Version Biotin & Other Labeled Version
This protein carries a polyhistidine tag at the C-terminus, followed by a twin strep tag.
The protein has a calculated MW of 30.1 kDa & 34.1 kDa. The protein migrates as 38-43 kDa and 55-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
Less than 1.0 EU per μg by the LAL method / rFC method.
Purity
>90% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
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Performance Data
SDS-PAGE

Cynomolgus IL-2 R beta&IL-2 R gamma Heterodimer Protein, His Tag&Twin-Strep Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).
SEC-MALS

The purity of Cynomolgus IL-2 R beta&IL-2 R gamma Heterodimer Protein, His Tag&Twin-Strep Tag (Cat. No. ILG-C5284) is more than 90% and the molecular weight of this protein is around 90-120 kDa verified by SEC-MALS.
Report
Bioactivity-ELISA

Immobilized Cynomolgus IL-2, His Tag (Cat. No. IL2-C5249) at 5 μg/mL (100 μL/well) can bind Cynomolgus IL-2 R beta&IL-2 R gamma Heterodimer Protein, His Tag&Twin-Strep Tag (Cat. No. ILG-C5284) with a linear range of 1-78 ng/mL (QC tested).
Protocol
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Background
Recent Advances
- English Name:
Interleukin-2 receptor subunit gamma
- Category:
- Approved Drugs:
0 Details
- Drugs in Clinical Trials:
14 Details
- Highest Development Stage:
Phase 2 Clinical
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