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製品詳細
Synonyms
IL2RG, CD132, CIDX, IMD4, P64, SCIDX, SCIDX1, gammaC
Source
Rhesus macaque IL-2 R gamma Protein, His Tag (ILG-R52H3) is expressed from human 293 cells (HEK293). It contains AA Leu 23 - Pro 255 (Accession # Q38JL2-1).
Predicted N-terminus: Leu 23
Request for sequenceMolecular Characterization
Other Tags and Version Biotin & Other Labeled Version
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 29.4 kDa. The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
Less than 1.0 EU per μg by the LAL method / rFC method.
Purity
>95% as determined by SDS-PAGE.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System
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データ表示
SDS-PAGE
Rhesus macaque IL-2 R gamma Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
SEC-MALS
The purity of Rhesus macaque IL-2 R gamma Protein, His Tag (Cat. No. ILG-R52H3) is more than 85% and the molecular weight of this protein is around 50-65 kDa verified by SEC-MALS.
Report
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バックグランド
Interleukin-2 receptor subunit gamma (IL2RG), also known as cytokine receptor common subunit gamma, CD antigen CD132, gammaC, p64, which belongs to the type I cytokine receptor family or type 5 subfamily. IL2RG is located on the surface of immature blood-forming cells in bone marrow. Defects in IL2RG are the cause of severe combined immunodeficiency X-linked T-cell-negative/B-cell-positive/NK-cell-negative (XSCID).
最新の進展
医薬品開発の進捗- 英語名：
Interleukin-2 receptor subunit gamma
- カテゴリ：
- 市販の医薬品数：
0 詳細
- 治験医薬品数：
14 詳細
- 最新の開発ステージ：
Phase 2 Clinical
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