Product Details
Synonyms
IL7Ra, CD127, TSLP R, CRLF2, IL-XR, ILXR, p2RY8, CRLF2 fusion, TSLP receptor, TSLPR, CRL2, CRLF2Y, Cytokine receptor-like 2
Source
Mouse IL-7 RA&TSLP R Heterodimer Protein, Fc Tag&Fc Tag (ILR-M5257) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Asp 239 (IL-7 RA) & Ala 20 - Pro 232 (TSLP R) (Accession # P16872 (IL-7 RA) & Q8CII9 (TSLP R)).
Predicted N-terminus: Glu 21 (IL-7 RA) & Ala 20 (TSLP R)
Request for sequenceMolecular Characterization

Other Tags and Version Biotin & Other Labeled Version
Mouse IL-7 RA&TSLP R Heterodimer Protein, Fc Tag&Fc Tag is produced by co-expression of IL-7 RA and TSLP R, has a calculated MW of 51.5 kDa (IL-7 RA) & 48.8 kDa (TSLP R). Subunit IL-7 RA is fused with a human IgG1 Fc fragment at the C-terminus and subunit TSLP R is fused with a human IgG1 Fc fragment at the C-terminus. The protein migrates as 55-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
Less than 0.1 EU per μg by the LAL method / rFC method.
Purity
>90% as determined by SDS-PAGE.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
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Performance Data
SDS-PAGE

Mouse IL-7 RA&TSLP R Heterodimer Protein, Fc Tag&Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).
Bioactivity-ELISA

Immobilized Mouse TSLP, His Tag (Cat. No. TSP-M52H8) at 5 μg/mL (100 μL/well) can bind Mouse IL-7 RA&TSLP R Heterodimer Protein, Fc Tag&Fc Tag (Cat. No. ILR-M5257) with a linear range of 0.2-5 ng/mL (QC tested).
Protocol
Immobilized Biotinylated Mouse TSLP, His,Avitag (Cat. No. TSP-M82E3) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Mouse IL-7 RA&TSLP R Heterodimer Protein, Fc Tag&Fc Tag (Cat. No. ILR-M5257) with a linear range of 0.2-2 ng/mL (Routinely tested).
Protocol
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Background
Recent Advances
- English Name:
Interleukin-7 receptor subunit alpha
- Category:
- Approved Drugs:
0 Details
- Drugs in Clinical Trials:
8 Details
- Highest Development Stage:
Phase 2 Clinical
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