Human Kallikrein 11 / KLK-11 Protein, His Tag (active enzyme)

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Cat. No. / Size
Price
Qty
KL1-H52H5-100ug
$350.00
KL1-H52H5-1mg
$2500.00
ETA of in-stock products:2 business days

Product Details

  • Synonyms

    KLK11, Kallikrein-11, Hippostasin, hK11, PRSS20, TLSP

  • Source

    Human Kallikrein 11 Protein, His Tag (KL1-H52H5) is expressed from human 293 cells (HEK293). It contains AA Ile 54 - Asn 282 (Accession # Q9UBX7).

    Predicted N-terminus: Ile 54

    Request for sequence
  • Molecular Characterization

    Kallikrein 11 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 27.1 kDa. The protein migrates as 35-42 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Supplied as 0.2 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5 with glycerol as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • SDS-PAGE

    Kallikrein 11 SDS-PAGE

    Human Kallikrein 11 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • Bioactivity

    Measured by its ability to cleave a colorimetric peptide substrate, N-carbobenzyloxy-Lys-ThioBenzyl ester (Z-Lys-SBzl), in the presence of 5,5’Dithio-bis (2-nitrobenzoic acid) (DTNB). The specific activity is >700 pmol/min/μg (QC tested).

    Protocol

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Background

Kallikrein 11 (hK11) is a secreted serine protease belonging to the kallikrein-related peptidase family. As a multifunctional enzyme, it efficiently cleaves specific kallikrein substrates and plays roles in proteolytic processing, contributing to the activation and regulation of other proteins.

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