Human MOG Protein, His Tag, low endotoxin

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製品番号/仕様
価格
数量
MOG-H52H3-100ug
$385.00
MOG-H52H3-1mg (500ug X 2)
$2540.00
ETA of in-stock products:2 business days
総アイテム数 製品金額$ 0

製品詳細

  • Synonyms

    MOG, BTN6, BTNL11, MOGIG2, NRCLP7, Myelin oligodendrocyte glycoprotein

  • Source

    Human MOG, His Tag (MOG-H52H3) is expressed from human 293 cells (HEK293). It contains AA Gly 30 - Gly 154 (Accession # Q16653-1).

    Predicted N-terminus: Gly 30

    Request for sequence
  • Molecular Characterization

    MOG Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 16.2 kDa. The protein migrates as 20-24 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 0.01 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Shipping and Storage

    This product is shipped at ambient temperature.

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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データ表示

  • SDS-PAGE

    MOG SDS-PAGE

    Human MOG, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

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バックグランド

Myelin oligodendrocyte glycoprotein (MOG), is a single-pass transmembrane glycoprotein of the immunoglobulin (Ig) superfamily. MOG is a myelin protein exclusively expressed in the CNS at the outermost surface of myelin sheaths and oligodendrocyte membranes. This makes MOG a potential target of cellular and humoral immune responses in inflammatory demyelinating diseases. Due to its late postnatal developmental expression, MOG is an important marker for oligodendrocyte maturation.

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医薬品開発の進捗
  • 英語名:

    Myelin-oligodendrocyte glycoprotein

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  • 市販の医薬品数:

    0 詳細

  • 治験医薬品数:

    1 詳細

  • 最新の開発ステージ:

    Phase 2 Clinical

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