Human ROR2 / NTRKR2 Protein, His Tag, low endotoxin (MALS verified)

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Cat. No. / Size
Price
Qty
RO2-H52E5-50ug
$380.00
RO2-H52E5-1mg (500ug X 2)
$2855.00
ETA of in-stock products:2 business days

Product Details

  • Synonyms

    ROR2, NTRKR2

  • Source

    Human ROR2, His Tag (RO2-H52E5) is expressed from human 293 cells (HEK293). It contains AA Glu 34 - Gly 403 (Accession # NP_004551.1).

    Predicted N-terminus: Glu 34

    Request for sequence
  • Molecular Characterization

    ROR2 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 43.2 kDa. The protein migrates as 55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 0.01 EU per μg by the LAL method / rFC method.

  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • SDS-PAGE

    ROR2 SDS-PAGE

    Human ROR2, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    ROR2 SEC-MALS

    The purity of Human ROR2, His Tag (Cat. No. RO2-H52E5) is more than 85% and the molecular weight of this protein is around 40-65 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     ROR2 ELISA

    Immobilized Human ROR2, His Tag (Cat. No. RO2-H52E5) at 1 μg/mL (100 μL/well) can bind Anti-ROR2 Antibody, Human IgG1 with a linear range of 0.1-4 ng/mL (QC tested).

    Protocol

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Background

Tyrosine-protein kinase transmembrane receptor ROR2 is also known as Neurotrophic tyrosine kinase, receptor-related 2 (NTRKR2), which belongs to the protein kinase superfamily and Tyr protein kinase family and ROR subfamily. ROR2 is a homodimer protein, which can binds YWHAB or interact with WTIP. ROR2 may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development.

Recent Advances

 
Drug Development Progress
  • English Name:

    Tyrosine-protein kinase transmembrane receptor ROR2

  • Category:

  • Approved Drugs:

    0 Details

  • Drugs in Clinical Trials:

    1 Details

  • Highest Development Stage:

    Phase 2 Clinical

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