Cynomolgus SEZ6 Protein, His Tag, low endotoxin (MALS verified)

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製品番号/仕様
価格
数量
SE6-C52H4-100ug
$470.00
SE6-C52H4-1mg (500ug X 2)
$3460.00
ETA of in-stock products:2 business days
総アイテム数 製品金額$ 0

製品詳細

  • Synonyms

    BSRPC

  • Source

    Cynomolgus SEZ6 Protein, His Tag (SE6-C52H4) is expressed from human 293 cells (HEK293). It contains AA Leu 20 - His 927 (Accession # A0A2K5WPJ4-1).

    Predicted N-terminus: Leu 20

    Request for sequence
  • Molecular Characterization

    SEZ6 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 99.9 kDa. The protein migrates as 130-180 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 0.01 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

    >95% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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データ表示

  • SDS-PAGE

    SEZ6 SDS-PAGE

    Cynomolgus SEZ6 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    SEZ6 SEC-MALS

    The purity of Cynomolgus SEZ6 Protein, His Tag (Cat. No. SE6-C52H4) is more than 95% and the molecular weight of this protein is around 130-170 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     SEZ6 ELISA

    Immobilized Cynomolgus SEZ6 Protein, His Tag (Cat. No. SE6-C52H4) at 1 μg/mL (100 μL/well) can bind Anti-SEZ6 Antibody (SC17) with a linear range of 0.06-2 ng/mL (QC tested).

    Protocol
  • Bioactivity-SPR

     SEZ6 SPR

    Anti-SEZ6 Antibody (SC17) captured on Protein A Chip can bind Cynomolgus SEZ6 Protein, His Tag (Cat. No. SE6-C52H4) with an affinity constant of 72.9 nM as determined in SPR assay (Biacore 8K) (Routinely tested).

    Protocol

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バックグランド

May play a role in cell-cell recognition and in neuronal membrane signaling. Seems to be important for the achievement of the necessary balance between dendrite elongation and branching during the elaboration of a complex dendritic arbor. Involved in the development of appropriate excitatory synaptic connectivity.

最新の進展

 
医薬品開発の進捗
  • 英語名:

    Seizure protein 6 homolog

  • カテゴリ:

  • 市販の医薬品数:

    0 詳細

  • 治験医薬品数:

    2 詳細

  • 最新の開発ステージ:

    Phase 3 Clinical

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