製品詳細
Synonyms
Sortilin, SORT1, 100 kDa NT receptor, Glycoprotein 95, Gp95, Gp95LDLCQ6, Neurotensin receptor 3, NT3NTR3, Ntr3, sortilin 1,
Source
Biotinylated Human Sortilin Protein, His,Avitag (SON-H82E9) is expressed from human 293 cells (HEK293). It contains AA Ser 78 - Asn 755 (Accession # Q99523-1).
Predicted N-terminus: Ser 78
Request for sequenceMolecular Characterization

Other Tags and Version Biotin & Other Labeled Version
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).
The protein has a calculated MW of 79.3 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Labeling
Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
Protein Ratio
Passed as determined by the HABA assay / binding ELISA.
Purity
>95% as determined by SDS-PAGE.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System
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データ表示
SDS-PAGE

Biotinylated Human Sortilin Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
SEC-MALS

The purity of Biotinylated Human Sortilin Protein, His,Avitag (Cat. No. SON-H82E9) is more than 85% and the molecular weight of this protein is around 80-107 kDa verified by SEC-MALS.
Report
Bioactivity-SPR

Biotinylated Human Sortilin Protein, His,Avitag (Cat. No. SON-H82E9) captured on Biotin CAP-Series S Sensor Chip can bind Human Progranulin Protein, His Tag (Cat. No. PGN-H52H3) with an affinity constant of 0.355 μM as determined in a SPR assay (Biacore 8K) (QC tested).
Protocol
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最新の進展
- 英語名:
Sortilin
- カテゴリ:
- 市販の医薬品数:
0 詳細
- 治験医薬品数:
3 詳細
- 最新の開発ステージ:
Phase 2 Clinical
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