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MMAE

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MME-PLS104-ELISA
 MMAE ELISA

Immobilized Disitamab Vedotin at 1 μg/mL (100 μL/well) can bind HRP conjugated Mouse Anti-MMAE&MMAF Antibody, mAb (Cat. No. MME-PLS104) with a linear range of 0.5-16 ng/mL (QC tested).

MME-BLS104-MALS-HPLC
MMAE MALS images

The purity of Biotinylated Anti-MMAE&MMAF Antibody, Mouse IgG1 (Cat. No. MME-BLS104) is more than 90% and the molecular weight of this protein is around 135-165 kDa verified by SEC-MALS.

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Background

Monomethyl auristatin E (MMAE) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types. Anti-MMAE antibody is a Mouse monoclonal antibody. This antibody has been shown to work in applications such as: PK, PD, Immunoassay and ELISA.

Clinical and Translational Updates

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