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Your Position: ホーム > CCL5

CCL5

概要

Name:C-C motif chemokine 5
Target Synonym:Beta-Chemokine RANTES,Regulated Upon Activation, Normally T-Expressed, And Presumably Secreted,RANTES,TCP228,SIS-Delta,SISd,Small-Inducible Cytokine A5,D17S136E,T Cell-Specific Protein P228,EoCP,C-C Motif Chemokine 5,C-C Motif Chemokine Ligand 5,CCL5,Small Inducible Cytokine A5 (RANTES),Chemokine (C-C Motif) Ligand 5,T-Cell Specific RANTES Protein,T-Cell Specific Protein P288,Small Inducible Cytokine Subfamily A (Cys-Cys), Member 5,Eosinophil Chemotactic Cytokine,T-Cell-Specific Protein RANTES,S
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 2 Clinical

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製造番号 種類 製品説明 構造 純度 特徴
CC5-H5251 Human Human CCL5/RANTES Protein, Fc Tag (MALS verified)
CC5-H5251-structure
CC5-H5251-sds
ACRO Quality

生物活性データの一部

CC5-H5251-MALS-HPLC
CCL5 MALS images

The purity of Human CCL5, Fc Tag (Cat. No. CC5-H5251) is more than 85% and the molecular weight of this protein is around 71-96 kDa verified by SEC-MALS.

CC5-H5251-ELISA
CCL5 ELISA

Immobilized Human CXCL4, His Tag (Cat. No. CX4-H52H9) at 5 μg/mL (100 μL/well) can bind Human CCL5, Fc Tag (Cat. No. CC5-H5251) with a linear range of 0.156-2.5 μg/mL (QC tested).

Protocol

Synonym Name

EoCP,Eosinophil chemotactic cytokine,SIS-delta,Small-inducible cytokine A5,T cell-specific protein P228,TCP228,D17S136E, SCYA5,CCL5,C-C motif chemokine 5T-cell-specific protein RANTES

Background

C-C chemokine ligand 5 (CCL5), also known as RANTES, is a target gene of NF-kappaB, and is expressed by T lymphocytes, macrophages, platelets, synovial fibroblasts, tubular epithelium, and certain types of tumour cells. CCL5 plays a role in recruiting a variety of leukocytes into inflammatory sites including T cells, macrophages, eosinophils, and basophils. CCL5 activity is mediated through its binding to CCR1, CCR3, and mainly CCR5.

Clinical and Translational Updates

臨床試験情報

Name Research Code Research Phase Company Indications Clinical Trials
AFX-5931 AFX-5931 Phase 2 Clinical Afecta Pharmaceuticals Eczema Details

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